Results 71 to 80 of about 633,536 (317)

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

Advanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun, Haochen Yang, Qing Xu, Xingya Li, Jinxing Lou, Jianchun Duan, Jiachen Xu, Zhuqing Liu, Yong Xia, Zhicai Lin, Linlin Li, Dan Sun, Jiaguo Li, Tao Liu, Jun Guo, Wenfeng Xu, Weimin Zhu, Yi Liu, Boyang Sun, Jia Zhong, Lijie Rong, Qijun Qian, Chenqi Xu, Jie Wang   +23 more
wiley   +1 more source

Ecosystem‐Centered Robot Design: Toward Ecoresorbable Sustainability Robots (ESRs)

Advanced Science, EarlyView.
Robots exploring natural ecosystems can support monitoring and conservation, but must adopt ecosystem‐centered design to avoid pollution, waste, and damage. This review proposes guidelines for co‐designing ecoresorbable sustainability robots (ESRs), uniting materials, robotics, and ecological contexts in a single framework.
Tülin Yılmaz Nayır, Yuan Fang, Consuelo Contreras, Andrew K. Schulz, Florian Hartmann   +4 more
wiley   +1 more source

Soybean Auxin Transporter PIN3 Regulates Nitrate Acquisition to Improve Nitrogen Use and Seed Traits

Advanced Science, EarlyView.
Xu et al. discovers that switching off auxin transporters in soybean, PIN3a and PIN3b, disrupts auxin flow; this triggers ARF‐STF3/4 signal cascade to activate the nitrate importer NPF2.13 and soil nitrogen acquisition. Multi‐year field trials show edited soybeans maintain yield with higher oil content, offering a potential genetic route to improve ...
Huifang Xu, Shiyu Huang, Jie Wang, Tian Wang, Qingqing Han, Kexin Wu, Zhen Gao, Xiaolei Shi, Tianli Tu, Ming Wang, Laimei Huang, Jiaomei Chen, Yunqi Liu, Yumei Zhang, Guoqiang Lin, Zhichang Chen, Xu Chen   +16 more
wiley   +1 more source

TÜRKİYE’NİN GÜNEYDOĞUSUNDA NÜFUSUN ZORUNLU YERİNDEN OLUŞU: SÜREÇLER ve MEKÂNSAL ÖRÜNTÜ

Coğrafi Bilimler Dergisi, 2006
Turkey is a country known for the geographical mobility of its population and it is one of the most important events that Turkey has dramatically experienced in terms of demography within the past two decades.
M. Murat Yüceşahin, E. Murat Özgür
doaj   +1 more source

Violent behaviour among Turkish high school students and correlates of physical fighting [PDF]

, 2004
Mehmet Alikaşifoğlu
openalex   +1 more source

Rigid Hollow Microparticles for Enhanced Focused Ultrasound Treatment Under Optoacoustic Guidance

Advanced Science, EarlyView.
By combining focused ultrasound (FUS) and acoustically active hollow borosilicate microparticles (HBMPs), we demonstrate tunable control over interparticle dynamics and their localized thermal energy deposition. Modulation of acoustic frequency and particle concentration tailors the energy delivery, allowing adaptive, material‐based regulation of ...
Nima Mahkam, Yi Chen, Héctor Estrada, Ananya Amitabh, Amirreza Aghakhani, Metin Sitti, Daniel Razansky   +6 more
wiley   +1 more source

BÖLGESEL GELİŞMEDE BİR ARAÇ OLARAK GİRİŞİMCİLİK: İL BAZINDA GİRİŞİMCİLİK EKOSİSTEMİNİN ÖLÇÜMÜ

Mehmet Akif Ersoy Üniversitesi İktisadi ve İdari Bilimler Fakültesi Dergisi, 2018
1970’lerdenitibaren esnek uzmanlaşma, bilgi ve iletişim teknolojilerindeki gelişmeler;yenilikçilik, KOBİ’lerin gücünü artırmasına imkân vermiştir.
SENAY Oğuztimur, Ebru Seçkin
doaj   +1 more source

Comparative study of biological activities and multicomponent pattern of two wild Turkish species: Asphodeline anatolica and Potentilla speciosa [PDF]

, 2016
Gökhan Zengin, Luigi Menghini, Luciano Malatesta, Elisa De Luca, Giuseppe Bellagamba, Şengül Uysal, Abdurrahman Aktümsek, Marcello Locatelli   +7 more
openalex   +1 more source

Contesting the “Corrupt Elites,” Creating the “Pure People,” and Renegotiating the Hierarchies of the International Order? Populism and Foreign Policy-Making in Turkey and Hungary

, 2021
Fulya Hisarlıoğlu, Lerna K. Yanık, Umut Korkut, İlke Civelekoğlu   +3 more
openalex   +2 more sources

Contribution of Gli1+ Adventitial Stem Cells to Smooth Muscle Cells in Atherosclerosis and Vascular Injury

Advanced Science, EarlyView.
Gli1+ adventitial stem cells (ASCs) have been thought to generate smooth muscle cells (SMCs) in atherosclerosis. Using a dual‐recombinase lineage tracing to exclude ectopic labeling, Wang et al. found that Gli1+ ASCs do not contribute to SMCs in atherosclerotic plaques.
Haixiao Wang, Xiuzhen Huang, Jialing Mou, Enci Wang, Yan Li, Wenjuan Pu, Yao Xie, Xiaoling Guo, Lixin Wang, Maoping Chu, Bin Zhou, Chao Niu   +11 more
wiley   +1 more source