Results 101 to 110 of about 2,795,245 (298)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Cooperation and coordination in the turn-taking dilemma [PDF]
Proceedings of the 9th conference on Theoretical aspects of rationality and knowledge, 2003 In many real-world situations, "cooperation" in the simple sense of the Prisoner's Dilemma is not sufficient for success: instead, cooperators must precisely coordinate more complex behaviors in a noisy environment. We investigate one such model, the Turn-Taking Dilemma, a variant of the repeated Prisoner's Dilemma in which the highest total payoff is ...
openaire +1 more source
Astrocyte heterogeneity in brain metastases
Molecular Oncology, EarlyView.Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver +2 more
wiley +1 more source
Realizations of turn-taking in conversational interactions [PDF]
, 2008 : The most common kind of spoken language is conversation, when one person communicates through speaking to another or to other people. In this paper, the author tries to give an account of how turn-taking is realized in conversational interactions ...
Yang Wei-dong
core
TURN TAKING IN INDONESIA TRADITIONAL MARKE
TRANSFORM: Journal of English Language Teaching and Learning, 2019 This current study aimed to examine the turn-taking strategies that are used by sellers and buyers at Horas traditional market, Pematangsiantar. This study wants to show the process of turn-taking between sellers and buyers when taking their turn. Especially on take the turn when sellers and buyers do bargaining process. It means that which can look at
Simanjuntak, Friska, Meisuri, Meisuri
openaire +2 more sources
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Turn-Taking in Nicaraguan Sign Language [PDF]
Across languages, individuals seem to plan turn-taking in conversations to minimize gaps and overlap (Sack et al., 1974). If turn-taking systems are a fundamental feature of language use, we should expect to see these signatures in different languages ...
Jennie Pyers +2 more
core +3 more sources
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Adaptability and Diversity in Simulated Turn-taking Behavior
Artificial Life, 2004 Turn-taking behavior is simulated in a coupled-agents system. Each agent is modeled as a mobile robot with two wheels. A recurrent neural network is used to produce the motor outputs and to hold the internal dynamics. Agents are developed to take turns on a two-dimensional arena by causing the network structures to evolve.
Hiroyuki Iizuka, Takashi Ikegami
openaire +3 more sources
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source