Results 21 to 30 of about 535,154 (272)

Biophysics of Tumor Microenvironment and Cancer Metastasis - A Mini Review

open access: yesComputational and Structural Biotechnology Journal, 2018
The role of tumor microenvironment in cancer progression is gaining significant attention. It is realized that cancer cells and the corresponding stroma co-evolve with time.
Bashar Emon   +4 more
doaj   +1 more source

Hetero-Diels–Alder Ligation (HDAL) of C20 Nanocage and Anti-Tumor Oxoindoline in Gas Phase and Solvent Phase, Using Density Functional Theory (DFT) [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2023
In this computational research, the solvent effect is probed on HDAL of C20 with I to yield Ia compound. So, in going from the gas phase to non-polar, and in turn to the polar solvent, a good consistency appears between the dielectric constant of the ...
Mohammad Poor Heravi   +6 more
doaj   +1 more source

Diet-induced obesity exacerbates auditory degeneration via hypoxia, inflammation, and apoptosis signaling pathways in CD/1 mice. [PDF]

open access: yesPLoS ONE, 2013
The aim of this study was to investigate the mechanisms of diet-induced obesity on hearing degeneration in CD/1 mice. Sixty 4-week-old male CD/1 mice were randomly and equally divided into 2 groups.
Juen-Haur Hwang   +4 more
doaj   +1 more source

TRIP13 is a protein-remodeling AAA+ ATPase that catalyzes MAD2 conformation switching. [PDF]

open access: yes, 2015
The AAA+ family ATPase TRIP13 is a key regulator of meiotic recombination and the spindle assembly checkpoint, acting on signaling proteins of the conserved HORMA domain family.
Corbett, Kevin D   +5 more
core   +2 more sources

Trace Element and Mineral Levels in Serum, Hair, and Urine of Obese Women in Relation to Body Composition, Blood Pressure, Lipid Profile, and Insulin Resistance

open access: yesBiomolecules, 2021
The objective of this study was to evaluate serum, hair, and urinary trace element and mineral content in normal-weight and obese women in relation to metabolic risk factors. A total of 80 women aged 30–70 y.o.
Alexey A. Tinkov   +7 more
doaj   +1 more source

Effect of boron on some organs of pregnant BALB/c mice [PDF]

open access: yesIraqi Journal of Veterinary Sciences, 2021
Current research had been conducted to assess the impact of boric acid (boron) on the different tissues of the fetal and maternal bodies of pregnant mice Mus musculus and its influence on the maternal plasma biochemistry, hematology, in addition to the ...
Baidaa A. Salah
doaj   +1 more source

Metallo-intercalators and metallo-insertors [PDF]

open access: yes, 2007
Since the elucidation of the structure of double helical DNA, the construction of small molecules that recognize and react at specific DNA sites has been an area of considerable interest.
Barton, Jacqueline K.   +2 more
core   +1 more source

Microbial Synthesis and Transformation of Inorganic and Organic Chlorine Compounds

open access: yesFrontiers in Microbiology, 2018
Organic and inorganic chlorine compounds are formed by a broad range of natural geochemical, photochemical and biological processes. In addition, chlorine compounds are produced in large quantities for industrial, agricultural and pharmaceutical purposes,
Siavash Atashgahi   +6 more
doaj   +1 more source

Isothermal calorimetry calscreener in the metabolism gauge of human malignant neoplastic cells: a burgeoning nexus in cancer biochemical metrology and diagnostics

open access: yesBulletin of the National Research Centre, 2023
Background At present, the function of isothermal microcalorimetry (IMC) calscreener in detecting alterations in the metabolic pathways of cancer cells remains unexplored.
Michael Tosin Bayode   +9 more
doaj   +1 more source

The retinoblastoma family of proteins and their regulatory functions in the mammalian cell division cycle

open access: yesCell Division, 2012
The retinoblastoma (RB) family of proteins are found in organisms as distantly related as humans, plants, and insects. These proteins play a key role in regulating advancement of the cell division cycle from the G1 to S-phases.
Henley Shauna A, Dick Frederick A
doaj   +1 more source

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