An unfolded protein-induced conformational switch activates mammalian IRE1. [PDF]
, 2017 The unfolded protein response (UPR) adjusts the cell's protein folding capacity in the endoplasmic reticulum (ER) according to need. IRE1 is the most conserved UPR sensor in eukaryotic cells.
Acosta-Alvear, Diego +5 more
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Conversations with chemists: information seeking behavior of chemistry faculty in the electronic age. [PDF]
, 2002 This manuscript is a final draft of the article as submitted to the Haworth journal Science and Technology Libraries in December 2002. Due to editorial error, Haworth published an earlier draft of this paper instead of the final draft.
Flaxbart, David
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AppliedChem, 2023 Living systems, whether healthy or diseased, must obey the laws of chemistry. The purpose of this review is to identify the interpretive limits of cellular biochemistry using, largely, the tools of physical chemistry.
Parker Schanen, Howard R. Petty
doaj +1 more source
Pathogenic mutations in the hydrophobic core of the human prion protein can promote structural instability and misfolding [PDF]
, 2010 Transmissible spongiform encephalopathies, or prion diseases, are caused by misfolding and aggregation of the prion protein PrP. These diseases can be hereditary in humans and four of the many disease-associated missense mutants of PrP are in the ...
Daggett, Valerie, van der Kamp, Marc W
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Atomic mutagenesis of stop codon nucleotides reveals the chemical prerequisites for release factor-mediated peptide release. [PDF]
, 2018 Termination of protein synthesis is triggered by the recognition of a stop codon at the ribosomal A site and is mediated by class I release factors (RFs).
Clementi, Nina +11 more
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Govindjee’s 90th birthday – Congratulations from friends and colleagues
Current Plant Biology, 2022 On the occasion of the 90th birthday of Govindjee, Professor Emeritus of Plant Biology, Biochemistry, and Biophysics, the University of Illinois at Urbana-Champaign (UIUC), over 100 celebrants have sent felicitations and messages to thank him for ...
Sushma Naithani +6 more
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What information on measurement uncertainty should be communicated to clinicians, and how? [PDF]
, 2018 open6embargoed_20190202Mario, Plebani*; Laura, Sciacovelli; Daniela, Bernardi; Ada, Aita; Giorgia, Antonelli; Andrea, PadoanPlebani, Mario; Sciacovelli, Laura; Bernardi, Daniela; Aita, Ada; Antonelli, Giorgia; Padoan ...
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Croatian Chemistry in the 20th Century. II. From the Collapse of Independent State of Croatia on May 8th, 1945 to the Establishment of the Republic of Croatia on June 25th, 1991 [PDF]
Kemija u Industriji, 2009 The development of Croatian chemistry from the end of the Second World War to the establishment of the Republic of Croatia is outlined. Briefly discussed is the founding and development of the Chemistry Department of the Faculty of Natural Sciences and ...
Vancik, H. +3 more
doaj
Unleashing the full potential of Hsp90 inhibitors as cancer therapeutics through simultaneous inactivation of Hsp90, Grp94, and TRAP1 [PDF]
, 2020 Cancer therapeutics: Extending a drug's reach A new drug that blocks heat shock proteins (HSPs), helper proteins that are co-opted by cancer cells to promote tumor growth, shows promise for cancer treatment.
Chae, Young Chan +10 more
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Nonprotein Structures from Mycobacteria: Emerging Actors for Tuberculosis Control
Clinical and Developmental Immunology, 2012 Immune response to Mycobacterium tuberculosis, the causal agent of tuberculosis, is critical for protection. For many decades, consistent to classical biochemistry, most studies regarding immunity to the tubercle bacilli focused mainly on protein ...
Luz M. Lopez-Marin
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