Results 41 to 50 of about 535,154 (272)

Developing a Bioinformatics Program and Supporting Infrastructure in a Biomedical Library

Journal of eScience Librarianship, 2018
Background: Over the last couple decades, the field of bioinformatics has helped spur medical discoveries that offer a better understanding of the genetic basis of disease, which in turn improve public health and save lives.
Nathan Hosburgh
doaj   +1 more source

Quantitative proteomic, physiological and biochemical analysis of cotyledon, embryo, leaf and pod reveals the effects of high temperature and humidity stress on seed vigor formation in soybean

BMC Plant Biology, 2020
Background Soybean developing seed is susceptible to high temperature and humidity (HTH) stress in the field, resulting in vigor reduction. Actually, the HTH in the field during soybean seed growth and development would also stress the whole plant ...
Jiaping Wei, Xiaolin Liu, Linzhi Li, Haihong Zhao, Sushuang Liu, Xingwang Yu, Yingzi Shen, Yali Zhou, Yajing Zhu, Yingjie Shu, Hao Ma   +10 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Biomarkers in Motor Neuron Disease: A State of the Art Review

Frontiers in Neurology, 2019
Motor neuron disease can be viewed as an umbrella term describing a heterogeneous group of conditions, all of which are relentlessly progressive and ultimately fatal.
Nick S. Verber, Stephanie R. Shepheard, Matilde Sassani, Harry E. McDonough, Sophie A. Moore, James J. P. Alix, Iain D. Wilkinson, Tom M. Jenkins, Pamela J. Shaw   +8 more
doaj   +1 more source

The study of association of serum ischemia-modified albumin and prediabetes in women: A case–control study

Asian Journal of Medical Sciences, 2022
Background: Prediabetes, diabetes, and their associated complications adversely affect women’s health worldwide. Women in the reproductive age group are more prone for developing diabetes and its associated complications such as gestational diabetes and ...
Ashok Kumar Ahirwar , Rashmi Jain , Udit Choubey , Ankit Jain , Roshan Takhelmayum , Apurva Sakarde , Akash Mahadeo Pawar , Bharatsing Deorao Rathod   +7 more
doaj   +1 more source

Cytochrome c signalosome in mitochondria [PDF]

, 2011
Cytochrome c delicately tilts the balance between cell life (respiration) and cell death (apoptosis). Whereas cell life is governed by transient electron transfer interactions of cytochrome c inside the mitochondria, the cytoplasmic adducts of cytochrome
Díaz Moreno, Irene, Díaz Quintana, Antonio Jesús, García Heredia, José Manuel, Rosa Acosta, Miguel Ángel de la   +3 more
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

The Anti-Inflammatory Effects of Cannabidiol (CBD) on Acne

Journal of Inflammation Research, 2022
Nadia Peyravian,1 Sapna Deo,1 Sylvia Daunert,1 Joaquin J Jimenez1,2 1Department of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, FL, USA; 2Phillip Frost Department of Dermatology & Cutaneous Surgery, University
Peyravian N, Deo S, Daunert S, Jimenez JJ   +3 more
doaj  

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Synthetic molecular switches driven by DNA-modifying enzymes

Nature Communications
Taking inspiration from natural systems, in which molecular switches are ubiquitous in the biochemistry regulatory network, we aim to design and construct synthetic molecular switches driven by DNA-modifying enzymes, such as DNA polymerase and nicking ...
Hong Kang, Yuexuan Yang, Bryan Wei
doaj   +1 more source