Results 61 to 70 of about 54,466 (294)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Epigenetics in Turner syndrome [PDF]

Clinical Epigenetics, 2018
أحادي الصبغي للكروموسوم X هو الشذوذ الوراثي الأكثر شيوعًا في الإنسان لأنه موجود في حوالي 2 ٪ من جميع المفاهيم، على الرغم من أن 99 ٪ من هذه الأجنة يتم إجهاضها تلقائيًا. في الحياة بعد الولادة، قد تشمل السمات السريرية لمتلازمة تيرنر وصمات تشوه نموذجية، وقصر القامة، والطفولة الجنسية، وتشوهات الكلى والقلب والهيكل العظمي والغدد الصماء والتمثيل الغذائي.
Francisco Álvarez‐Nava, Roberto Lanes
openaire   +3 more sources

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

A rare case of acute coronary syndrome in a patient with turner syndrome

Research in Cardiovascular Medicine, 2016
Introduction: In Turner syndrome, cardiovascular complications are the most important causes of early mortality. Congenital cardiovascular abnormalities are found in approximately one third of Turner syndrome patients.
Tugba Kemaloglu, Nihat Ozer, Mehmet Fikri Yapici   +2 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Management of Turner Syndrome [PDF]

US Endocrinology, 2015
Turner syndrome is one of the most common genetic disorders, affecting one in 2,000–2,500 live-born girls. In order to provide appropriate healthcare, a multi-disciplinary team of closely cooperating endocrinologists, gynaecologists, geneticists, cardiologists, otolaryngologists, fertility specialists, psychologists, nurse educators and social workers ...
openaire   +3 more sources

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Turner Syndrome: The Patients's View

, 2015
Objective: To identify how patients with Turner syndrome perceive their condition. Methods: Thirty-six women with Turner syndrome, aged between 15 and 25 years and with over 2 years of medical follow-up, were individually interviewed about: the impact of
Paiva E Silva R.B., Baptista M.T.M., Suzigan L.Z.C., Guerra Jr. G., Maciel Guerra A.T., Lemos Marini S.H.V., Magna L.A.   +6 more
core   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Turner Syndrome; A Case Report With Growth Failure

Endocrinology Research and Practice, 2022
Turner syndrome which afflicts approximately 50 per 100000 females is characterized by retarded growth, gonadal dysgenesis, and infertility. Growth failure is a consistent finding at birth in infants with Turner's syndrome.
Betül Ersoy, Şenol Coşkun, Erhun Kasırga, Ali Onağ   +3 more
doaj   +2 more sources