Results 91 to 100 of about 2,629,242 (377)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Characteristics of non‐fatal opioid overdoses attended by ambulance services in Australia

Australian and New Zealand Journal of Public Health, 2004
Objective: To examine the feasibility of establishing a database on non‐fatal opioid overdose in order to examine patterns and characteristics of these overdoses across Australia.
Paul Dietze, Damien Jolley, Stefan Cvetkovski, Kate Cantwell, Ian Jacobs, Devon Indig   +5 more
doaj   +1 more source

Sustainability and Efficiency: Comparative Analysis of Vegetable-Based and Synthetic Cutting Fluids in SAE 1045 Steel Turning [PDF]

Materials Research
The use of mineral oil-based fluids in machining processes can lead to social and environmental problems. Therefore, the objective of this study is to perform a comparative technical-economic analysis between biodegradable emulsions based on babassu oil,
Josean da S. Lima Junior, Yuri L. Santos, Kaciê K. A. Trindade, Maxime Montoya, Kleber G. B. Alves, Flávio J. da Silva   +5 more
doaj   +1 more source

Editorial -- Turn, turn, turn...

Electronic Green Journal, 1997
Author(s): Stoss, Frederick W.
openaire   +3 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Examining the relationships between eco-anxiety, sociodemographic factors, experience of climate events, pro-environmental behaviours, and life satisfaction in young adults

BMC Psychology
Background Climate change and environmental degradation pose significant threats to ecosystems and human well-being, leading to increased eco-anxiety, especially among young adults. Eco-anxiety, characterized by worry and fear about environmental issues,
Juan Roldán Merino, Antonio Moreno Poyato, María Eugenia Malleville, Camila Botero, Arantxa Y. Arredondo, Andrea Rodriguez Quiroga, Tiago Costa, Luísa Teixeira-Santos, Lara Guedes de Pinho, Carlos Sequeira, Sílvia Luís, Francisco Sampaio   +11 more
doaj   +1 more source

Multi-response optimization of CuZn39Pb3 brass alloy turning by implementing Grey Wolf algorithm

Fracture and Structural Integrity, 2019
Machinability of engineering materials is crucial for industrial manufacturing processes since it affects all the essential aspects involved, e.g. workload, resources, surface integrity and part quality. Two basic machinability parameters are the surface
Nikolaos Fountas, Angelos Koutsomichalis, John D. Kechagias, Nikolaos M. Vaxevanidis   +3 more
doaj   +1 more source

Manufacturing Parts for Hydraulic Systems of Agricultural Machinery under Conditions of Ultrasonic Cutting

Инженерные технологии и системы, 2020
Introduction. The article deals with the problem of reducing the efforts when processing thin-walled bushings for hydraulic systems of agricultural machines with the ultrasonically activated cutting tool to achieve the specified processing accuracy and ...
Vladimir A. Skryabin
doaj   +1 more source

To the Framingham Data, Turn, Turn, Turn [PDF]

Circulation, 2009
Beginning in the mid to late 1960s and continuing to the present, declines in the annual death rates attributed to coronary heart disease (CHD) have been observed in American men and women, reversing previously observed trends of steadily increasing mortality from CHD.1 Despite these encouraging trends, CHD continues to be a leading cause of morbidity ...
openaire   +2 more sources