Results 91 to 100 of about 475,288 (294)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Computer graphics techniques for modeling page turning

, 2007
Turning the page is a mechanical part of the cognitive act of reading that we do literally unthinkingly. Interest in realistic book models for digital libraries and other online documents is growing.
Witten, Ian H., Liesaputra, Veronica
core  

Effect of egg turning and incubation time on carbonic anhydrase gene expression in the blastoderm of the Japanese quail (Coturnix c. japonica)

, 2008
(1) The gene expression of carbonic anhydrase, a key enzyme for the production sub-embryonic fluid (SEF), was assessed in turned and unturned eggs of the Japanese quail.
Baggott, G. K., Baggott, Glenn K., Sugden, D, Sugden, D., de Winter, Patricia, De Winter, P.   +5 more
core   +1 more source

Influence of Tool-Workpiece Interface on Surface Integrity after Turning

Communications, 2014
This paper deals with influence of flank wear on decomposition of cutting force in turning roll bearing steel. The decomposition is carried out to evaluate the components of cutting force in the tool-chip as well as tool-workpiece interface.
Jaroslav Dubec, Miroslav Neslusan, Anna Micietova, Maria Cillikova   +3 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Investigations of Surface Roughness and Temperatures in Vegetable Oil-based n-MQL Turning of AISI 4340 Steel [PDF]

Journal of Engineering, Project, and Production Management
Machining of hard materials has been difficult and expensive because of poor surface smoothness, early tool failures, etc. When used in machining hard materials, such as medium and high carbon, cast steels, Inconel, and other alloys, nanomaterials ...
VeeraBhadraRao Miriyala, Bhushan T. Patil, Vasim A. Shaikh, D.S.S. Sudhakar, Sujata Deshmukh   +4 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Natural dye modification of polyethylene oxide: optical characterization and dielectric enhancement

Journal of Materials Science: Materials in Engineering
This study explores the optical properties of polyethylene oxide (PEO) modified with natural dye extracted from hollyhock (HH) flowers. This study is a green chemistry approach to reduce the optical band gap of PEO polymer.
Shujahadeen B. Aziz, Dana S. Muhammad, Sewara J. Mohammed, Daron Q. Muheddin, Shakhawan Al-Zangana, Ahang M. Hussein, Ary R. Murad, Govar H. Hamasalih, Samir M. Hamad, Dilshad Shaikhah   +9 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

A turning point chronology for the Euro-zone [PDF]

We propose a dating process for the business and growth Euro-zone cycles. This process is a result of a non parametric algorithm and diverse criteria assessment (duration, deepness, diffusion, synchronisation), as well as of “expert judgments” based on a
Marco Lo Duca, Jacques Anas, Monica Billio, Laurent Ferrara   +3 more
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