Results 31 to 40 of about 575,364 (288)
Introduction Opioid agonist treatment (OAT) is an evidence-based intervention that reduces harms associated with heroin use. Ambulance services often serve as the first point of contact for people experiencing these acute harms.
Natasha Hall +5 more
doaj +1 more source
A Simplistic Regression-Based Genetic Algorithm Optimization of Tool-Work Interface Temperature
This work aims to investigate the average tool-work interface temperature for the HSS tool and AISI 1040 steel pair. A tool-work thermocouple is proposed for the measurement of temperature because of its simple construction in addition to the low cost ...
Utkarsh . +5 more
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Background A large proportion of ambulance callouts are for men with mental health and/or alcohol and other drug (AOD) problems, but little is known about their experiences of care.
Nyssa Ferguson +8 more
doaj +1 more source
©2014 by the authors. This work is licensed under a Creative Commons License. JHM is a bi-annual journal sponsored by the Claremont Center for the Mathematical Sciences and published by the Claremont Colleges Library | ISSN 2159-8118 | http://scholarship.claremont.edu/jhm/ Recommended Citation Huber, Mark and Karaali, Gizem (2014) "Turn! Turn!
Mark Huber, Gizem Karaali
openaire +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Background Families have an important role supporting a family member with problematic substance use (PSU), although this can often be challenging and confronting.
Terence V. McCann +3 more
doaj +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source

