Results 51 to 60 of about 475,288 (294)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Electrolyte and Water Balance of the Early Avian Embryo: Effects of Egg Turning

, 2002
Formation of sub-embryonic fluid (SEF) is a key aspect of the physiology of the early avian embryo.Here we review the process of SEF formation and the factors which influence its composition and the rate of SEF production and depletion in the Japanese ...
Latter, G.V., Deeming, D.C., Baggott, Glenn K.   +2 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Pre-evaluation on surface profile in turning process based on cutting parameters [PDF]

, 2009
Traditional online or in-process surface profile (quality) evaluation (prediction) needs to integrate cutting parameters and several in-process factors (vibration, machine dynamics, tool wear, etc) for high accuracy.
MA, Ning, LU, Chen, CHEN, Zhuo, COSTES, Jean-Philippe   +3 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Turning Points in Negotiation

, 2011
This manuscript will appear as a State of the Art Commentary about turning points in ...
Olekalns, Mara, Druckman, Daniel, Mara Olekalns, Daniel Druckman   +3 more
core   +1 more source

The therapist experience of internet delivered CBT for problem gambling: Service integration considerations

Internet Interventions, 2019
Introduction: Countries with legalized gambling offer a network of government funded face-to-face therapy, but usage of this expertise is on the decline.
S.N. Rodda, S. Merkouris, T. Lavis, D. Smith, D.I. Lubman, D. Austin, P. Harvey, M. Battersby, N.A. Dowling   +8 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Paramedic perceptions of decision-making when managing mental health-related presentations: a qualitative study

BMC Medical Informatics and Decision Making
Background Mental health presentations account for a considerable proportion of paramedic workload; however, the decision-making involved in managing these cases is poorly understood.
Kate Emond, George Mnatzaganian, Michael Savic, Dan I. Lubman, Melanie Bish   +4 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source