Results 121 to 130 of about 6,963,187 (336)
Solitons and Black Holes in a Generalized Skyrme Model with Dilaton-Quarkonium field
, 2012 Skyrme theory is among the viable effective theories which emerge from low-energy limit of quantum chromodynamics. Many of its generalizations include also a dilaton.
A. A. Andrianov +6 more
core +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Quantum counterpart of spontaneously broken classical PT symmetry
, 2010 The classical trajectories of a particle governed by the PT-symmetric Hamiltonian $H=p^2+x^2(ix)^\epsilon$ ($\epsilon\geq0$) have been studied in depth.
Bender C M +5 more
core +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Rule of law and the Environmental Kuznets Curve: evidence for carbon emissions [PDF]
In response to recently growing literature investigating the relationship between environment and institutions, this study investigates how rule of law influences the level of income at the turning point of the Environmental Kuznets Curve (EKC). Using an
Concetta Castiglione +2 more
core
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Optics Express, 2018 In most fiber-optic gas sensing applications where the interested refractive index (RI) is ~1.0, the sensitivities are greatly constrained by the large mismatch between the effective RI of the guided mode and the RI of the surrounding gaseous medium ...
N. Zhang +7 more
semanticscholar +1 more source
Rest frame of bubble nucleation
, 2013 Vacuum bubbles nucleate at rest with a certain critical size and subsequently expand. But what selects the rest frame of nucleation? This question has been recently addressed in [1] in the context of Schwinger pair production in 1+1 dimensions, by using ...
Garriga, Jaume +2 more
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source