Results 31 to 40 of about 1,412,477 (278)

Living with an iconic aid

open access: yesCulture Unbound: Journal of Current Cultural Research, 2023
There are plenty of objects that are conspicuous in the way they signal to the surroundings that the user has some kind of physical impairment. Most obvious are perhaps wheelchairs, motorized wheelchairs, hearing aids and crutches.
Maria Bäckman
doaj   +1 more source

Turning points or turning around: Family coach work with 'troubled families' [PDF]

open access: yes, 2015
The study aimed to discover how family coaches work intensively with families with moderately complex problems bringing together perceptions from 20 families, 20 coaches and six other professionals, and exploring potential savings for 50 family cases ...
Bailey, Susan   +4 more
core  

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Turning points during the life of student project teams: A qualitative study

open access: yesFrontline Learning Research, 2015
In this qualitative study a more flexible alternative of conceptualising changes over time in teams is tested within student project teams. The conceptualisation uses turning points during the lifespan of a team to outline team development, based on work
Elisabeth Raes, Filip Dochy, Eva Kyndt
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

The Process of Becoming an Activist: Identity Transformations in Autobiographical Narratives of Women with Disabilities in Poland

open access: yesPrzeglad Socjologii Jakosciowej, 2023
This article reconstructs identity transformations that manifest themselves in the biographies of female activists with disabilities. The empirical material was collected through autobiographical narrative interviews. The author identifies key stages and
Kamila Albin
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Predicting turning points in the South African economy

open access: yesSouth African Journal of Economic and Management Sciences, 2003
Despite the existence of macroeconomic models and complex business cycle indicators, it would be beneficial to policymakers and market participants if they could look at one well-chosen indicator in predicting business cycle turning points.
Elna Moolman
doaj   +1 more source

A High-Order Method for Stiff Boundary Value Problems with Turning Points [PDF]

open access: yes, 1987
This paper describes some high-order collocation-like methods for the numerical solution of stiff boundary-value problems with turning points. The presentation concentrates on the implementation of these methods in conjunction with the implementation of ...
Brown, David L., Lorenz, Jens
core   +1 more source

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