Results 81 to 90 of about 86,843,930 (201)

THESS‐ROP study: Development of a prediction model for treatment‐warranted retinopathy of prematurity and external validation of postnatal weight‐gain‐based models in Greece

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To develop THESS‐ROP, a novel prediction model for treatment‐warranted retinopathy of prematurity (TW‐ROP) and compare its performance with four established models in a Greek cohort of consecutively screened preterm infants. Methods This ambispective cohort study included all 526 infants screened for ROP (2016–2022) at the 2nd ...
Stella Moutzouri   +6 more
wiley   +1 more source

Clinical Outcomes After Percutaneous Coronary Intervention in Patients With Cirrhosis: A Multicentre National Study

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
Summary of a multicentre TriNetX study evaluating outcomes after percutaneous coronary intervention (PCI) in patients with cirrhosis. Cirrhosis was associated with higher 1‐year gastrointestinal bleeding and mortality, especially with decompensated disease.
Dhir Gala   +13 more
wiley   +1 more source

Red lines and green lights: Gene therapy for inherited erythroid disorders beyond the haemoglobinopathies

open access: yesBritish Journal of Haematology, EarlyView.
Gene therapy is revolutionizing treatment paradigms for haemoglobinopathies, establishing a translational framework for disorders that impact red blood cell development. In their paper, Joshi et al. describe the preclinical and early clinical landscape of gene therapies for non‐haemoglobinopathy erythroid disorders and highlight common thematic ...
Gaurav Joshi   +3 more
wiley   +1 more source

The association between inborn errors of immunity and Hodgkin lymphoma—A register‐based case–control study in Sweden

open access: yesBritish Journal of Haematology, EarlyView.
Summary Immune dysfunction is implicated in the aetiology of Hodgkin lymphoma (HL), but the association between inborn errors of immunity (IEI) and HL remains poorly understood. We conducted a retrospective, register‐based case–control study in Sweden over five decades to investigate the relationship between IEI and HL. Individuals diagnosed with HL in
Agnes Winsa   +7 more
wiley   +1 more source

Distinct clinical and genetic characteristics of myelodysplastic syndrome in younger patients

open access: yesBritish Journal of Haematology, EarlyView.
Summary Myelodysplastic neoplasms (formerly myelodysplastic syndromes, MDS) are heterogeneous clonal haematological malignancies that primarily affect the elderly, though a notable proportion of patients are diagnosed at younger ages. We retrospectively analysed 1437 patients diagnosed or treated at Asan Medical Center between 1989 and 2022, comparing ...
Hyunkyung Park   +15 more
wiley   +1 more source

Twin to twin transfusion syndrome presenting at early stages: is there still a possibile role for amnioreduction.

open access: yes, 2009
OBJECTIVE: To assess the rate of resolution or progression after first line treatment with amnioreduction and related outcome of pregnancies with twin-to-twin transfusion syndrome (TTTS) diagnosed at stages I-II.
M. Rustico   +4 more
core   +1 more source

Real‐world outcomes of ide‐cel and cilta‐cel in relapsed/refractory multiple myeloma: A nationwide, retrospective analysis in Austria

open access: yesBritish Journal of Haematology, EarlyView.
Summary B‐cell maturation antigen‐directed chimeric antigen receptor (CAR) T cells have revolutionized the treatment of relapsed/refractory multiple myeloma. However, no randomized head‐to‐head comparison of idecabtagene vicleucel (ide‐cel) and ciltacabtagene autoleucel (cilta‐cel) is available, and real‐world data suggest differences in efficacy and ...
Irene Strassl   +23 more
wiley   +1 more source

Autoimmune neutropenia in children: Test cells versus beads and a role for pro‐LL‐37 and absolute neutrophil count

open access: yesBritish Journal of Haematology, EarlyView.
A comparison between bead‐based and cell‐based assays for autoantibody detection in childhood neutropenia revealed substantial discordance between platforms. Bead‐based methods should be complemented with cell‐based methods for optimal diagnostic sensitivity. Incorporating pro‐LL‐37 and ANC measurements into the clinical workup of childhood neutropenia
Paul Ratcliffe   +3 more
wiley   +1 more source

Parvovirus B19 infections in paediatric sickle cell disease patients: Genotype and hydroxyurea treatment influence disease severity

open access: yesBritish Journal of Haematology, EarlyView.
Summary In patients with sickle cell disease (SCD), parvovirus B19 infection (B19V) leads to acute anaemia (aplastic crisis), but may also be associated with other serious complications. We retrospectively analysed clinical data from paediatric SCD patients with B19V infections between 2023 and 2025, including symptoms, laboratory parameters ...
Matthias Bleeke   +42 more
wiley   +1 more source

Optimizing cord blood unit selection to improve survival after single‐unit unrelated cord blood transplantation for adult myelodysplastic syndrome

open access: yesBritish Journal of Haematology, EarlyView.
Summary Unrelated cord blood transplantation (CBT) is an important alternative donor option for adult patients with myelodysplastic syndrome (MDS); however, the prognostic significance of cord blood unit characteristics following CBT remains unclear and may vary according to disease risk.
Takaaki Konuma   +23 more
wiley   +1 more source

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