Results 211 to 220 of about 49,659 (292)

Non-right-handedness and psychiatric disorders: A synthesis of epidemiological, genetic, and neurobiological evidence. [PDF]

World J Psychiatry
Wang QQ, Sun ZS, Wang JS.
europepmc   +1 more source

Compensatory Interplay Between Clarin‐1 and Clarin‐2 Deafness‐Associated Proteins Governs Phenotypic Variability in Hearing

Advanced Science, EarlyView.
Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling, Aïda Yakhlef Sanchez, Nicolas Thelen, Müge Senarisoy, Maria Hogg, Steven Condamine, Andrea Lelli, Emilia Wysocka, Pranav Patni, Sandrine Vitry, Kerem Yasin Yildizhan, Sébastien Le Gal, Sylvie Nouaille, Michael R. Bowl, Marc Thiry, Didier Dulon, Sedigheh Delmaghani, Aziz El‐Amraoui   +17 more
wiley   +1 more source

Systematic Engineering of Proteases in Saccharopolyspora Spinosa Reveals Synergistic Enhancement of Spinosad Biosynthesis via Substrate Flux Optimization

Advanced Science, EarlyView.
ARTP mutagenesis yielded Saccharopolyspora spinosa mutant D184 with improved extracellular nitrogen utilization. An integrated workflow of protease genetic manipulation, multi‐omics, and rational synergy design pinpointed a pepP‐clpP‐htpX synergistic triangular combination.
Duo Jin, Wangqiong Chen, Danlu Yang, Qing Liu, Baolong Bai, Zirui Dai, Xirong Liu, Zirong Zhu, Jie Rang, Liqiu Xia   +9 more
wiley   +1 more source

Myopia is predominantly genetic or predominantly environmental? [PDF]

Ophthalmic Physiol Opt
Verhoeven VJM, Morgan IG, Guggenheim JA.
europepmc   +1 more source

Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare

Advanced Science, EarlyView.
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu, Haolin Fan, Minwoo Kim, Tong Zhou, Pinyi Yang, Lingdi Zhao, Yiran Wang, Ziyuan Che, Chia‐Wei Liu, Bingbing Li, Yangzhi Zhu   +10 more
wiley   +1 more source

Beyond the sum of their parts: A multi-dimensional approach to dyscalculia-dyslexia comorbidity integrating studies of the brain, behavior, and genetics. [PDF]

Dev Cogn Neurosci
Starling-Alves I, Peters L, Wilkey ED.
europepmc   +1 more source

A CLE11b‐CLE16 Signaling Relay Mediates Root‐Shoot‐Root Crosstalk for Drought Adaptation in Common Bean

Advanced Science, EarlyView.
A novel root‐shoot‐root signaling relay, mediated by CLE peptides, coordinates drought adaptation in common bean. Root‐derived PvCLE11b translocates acropetally to leaves, inducing PvCLE16 expression via PvTCP10. Leaf‐accumulated PvCLE16 triggers stomatal closure and translocates basipetally to modulate root architecture.
Xinyang Wu, Shiyuan Tao, Zhuoyi Wang, Ting Sun, Zixin Zhang, Su Yang, Min Xu, Chenyi Huang, Siyi Wang, Xubo Ke, Chenze Lu, Kang Ning, Pei Xu   +12 more
wiley   +1 more source

Unveiling autism spectrum disorder for the pediatrician. [PDF]

J Pediatr (Rio J)
Vasconcelos MM, Vasconcelos LGA, Brito AR.   +2 more
europepmc   +1 more source

Highly Active IrRuOx/MnOx Electrocatalysts with Ultralow Anode PGM Demand in Proton Exchange Membrane Electrolyzers

Advanced Energy Materials, EarlyView.
MnOx‐supported IrRuOx exhibits outstanding OER performance in both liquid electrolytes and real cell environments. The MnOx not only enhances the dispersion of IrRuOx but also induces a compressive strain effect. The incorporation of Ru leads to surface reconstruction.
Jiaqi Kang, Sebastian Möhle, Xingli Wang, Miklós Márton Kovács, Kerolus Nasser Nagi Nasralla, Johannes Schmidt, Sören Selve, Dominik Dworschak, Peter Strasser   +8 more
wiley   +1 more source

Unraveling ADHD for the pediatrician. [PDF]

J Pediatr (Rio J)
Casella EB, Casella BB.
europepmc   +1 more source