Results 211 to 220 of about 40,784 (286)

Compensatory Interplay Between Clarin‐1 and Clarin‐2 Deafness‐Associated Proteins Governs Phenotypic Variability in Hearing

Advanced Science, EarlyView.
Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling, Aïda Yakhlef Sanchez, Nicolas Thelen, Müge Senarisoy, Maria Hogg, Steven Condamine, Andrea Lelli, Emilia Wysocka, Pranav Patni, Sandrine Vitry, Kerem Yasin Yildizhan, Sébastien Le Gal, Sylvie Nouaille, Michael R. Bowl, Marc Thiry, Didier Dulon, Sedigheh Delmaghani, Aziz El‐Amraoui   +17 more
wiley   +1 more source

Study of Chemosensory Enhancement through Neuromodulation Training (SCENT): Design and methodology of a randomized clinical trial for COVID-related persistent smell dysfunction. [PDF]

Contemp Clin Trials Commun
Cash N, Koebel MC, Badran BW, Schumann AY, McTeague LM, Uhde TW, Schlosser RJ, Cortese BM.   +7 more
europepmc   +1 more source

Systematic Engineering of Proteases in Saccharopolyspora Spinosa Reveals Synergistic Enhancement of Spinosad Biosynthesis via Substrate Flux Optimization

Advanced Science, EarlyView.
ARTP mutagenesis yielded Saccharopolyspora spinosa mutant D184 with improved extracellular nitrogen utilization. An integrated workflow of protease genetic manipulation, multi‐omics, and rational synergy design pinpointed a pepP‐clpP‐htpX synergistic triangular combination.
Duo Jin, Wangqiong Chen, Danlu Yang, Qing Liu, Baolong Bai, Zirui Dai, Xirong Liu, Zirong Zhu, Jie Rang, Liqiu Xia   +9 more
wiley   +1 more source

Fetal Safety of Intravenous Ferric Carboxymaltose in Pregnancy: A Cardiotocography Study from a Tertiary Care Hospital in Italy. [PDF]

Hematol Rep
Polese F, Pesce C, De Fusco G, Tidore G, Coluccia E, Battista R, Gessoni G.   +6 more
europepmc   +1 more source

Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare

Advanced Science, EarlyView.
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu, Haolin Fan, Minwoo Kim, Tong Zhou, Pinyi Yang, Lingdi Zhao, Yiran Wang, Ziyuan Che, Chia‐Wei Liu, Bingbing Li, Yangzhi Zhu   +10 more
wiley   +1 more source

Neurocognition, cerebellar functions and psychiatric features in spinocerebellar ataxia type 34: a case series. [PDF]

Front Comput Neurosci
Cundari M, Kirchhoff L, Vestberg S, van Westen D, Dobloug S, Markenroth Bloch K, Nilsson M, Wennberg L, Hansson B, Priovoulos N, Rasmussen A, Gorcenco S.   +11 more
europepmc   +1 more source

A CLE11b‐CLE16 Signaling Relay Mediates Root‐Shoot‐Root Crosstalk for Drought Adaptation in Common Bean

Advanced Science, EarlyView.
A novel root‐shoot‐root signaling relay, mediated by CLE peptides, coordinates drought adaptation in common bean. Root‐derived PvCLE11b translocates acropetally to leaves, inducing PvCLE16 expression via PvTCP10. Leaf‐accumulated PvCLE16 triggers stomatal closure and translocates basipetally to modulate root architecture.
Xinyang Wu, Shiyuan Tao, Zhuoyi Wang, Ting Sun, Zixin Zhang, Su Yang, Min Xu, Chenyi Huang, Siyi Wang, Xubo Ke, Chenze Lu, Kang Ning, Pei Xu   +12 more
wiley   +1 more source

Disruptions in Reward-Guided Decision-Making Functions Are Predictive of Greater Oral Oxycodone Self-Administration in Male and Female Rats. [PDF]

Biol Psychiatry Glob Open Sci
LaRocco K, Villiamma P, Hill J, Russell MA, DiLeone RJ, Groman SM.   +5 more
europepmc   +1 more source

Highly Active IrRuOx/MnOx Electrocatalysts with Ultralow Anode PGM Demand in Proton Exchange Membrane Electrolyzers

Advanced Energy Materials, EarlyView.
MnOx‐supported IrRuOx exhibits outstanding OER performance in both liquid electrolytes and real cell environments. The MnOx not only enhances the dispersion of IrRuOx but also induces a compressive strain effect. The incorporation of Ru leads to surface reconstruction.
Jiaqi Kang, Sebastian Möhle, Xingli Wang, Miklós Márton Kovács, Kerolus Nasser Nagi Nasralla, Johannes Schmidt, Sören Selve, Dominik Dworschak, Peter Strasser   +8 more
wiley   +1 more source

Cerebral oximetry monitoring versus usual care for extremely preterm infants: a detailed statistical analysis plan for the 2-year follow-up of the participants of the SafeBoosC-III randomised clinical trial. [PDF]

Trials
Rasmussen MIS, Hansen ML, Pellicer A, Gluud C, Dempsey E, Mintzer J, Hyttel-Sørensen S, Heuchan AM, Hagmann C, Ergenekon E, Dimitriou G, Pichler G, Naulaers G, Tkaczyk J, Fuchs H, Fumagalli M, Nesargi S, Fredly S, Szczapa T, Plomgaard AM, Hansen BM, Olsen MH, Jakobsen JC, Greisen G.   +23 more
europepmc   +1 more source