Results 91 to 100 of about 2,453,712 (230)

1,2‐propanediol reformulation improves tribromoethanol safety and reveals pontine GABRA1 enrichment as a candidate mechanistic correlate of anesthesia

Animal Models and Experimental Medicine, EarlyView.
This study develops a reformulated tribromoethanol (TBE) anesthetic using 1,2‐propanediol as a solvent to overcome solvent‐related toxicity. The novel formulation demonstrates, cardiovascular stability, and survival in prolonged protocols. It provides potent, dose‐dependent anesthesia without strain or sex differences.
Xia Li, Yanming Chen, Xinyi Xiao, Guoheng Xu   +3 more
wiley   +1 more source

Neutrophil Extracellular Traps Block Fibrinolysis in Ischemic Stroke

Annals of Neurology, EarlyView.
Objectives Intravenous thrombolysis (IVT) failure in acute ischemic stroke (AIS) is frequent, but its causes remain elusive. We investigated whether biologically relevant intrathrombus concentrations of tissue plasminogen activator (tPA) were achieved in failed IVT and whether neutrophil extracellular traps (NETs) contributed to this therapeutic ...
Mialitiana Solo Nomenjanahary, Jean‐Philippe Desilles, Fatima Zemali, Astride Perrot, Lucas Di Meglio, Sara Zalghout, Jéromine Fasille, Jérémy Neel, Stéphane Loyau, Julien Labreuche, Marie‐Charlotte Bourrienne, Dorothée Faille, François Delvoye, Véronique Ollivier, Sébastien Dupont, Jasmina Rogozarski, Nahida Brikci‐Nigassa, Robert L. Medcalf, Nadine Ajzenberg, Mikael Mazighi, Benoît Ho‐Tin‐Noé, the compoCLOT Study Group   +21 more
wiley   +1 more source

Trap Sequence: Case Report

Gynecology Obstetrics & Reproductive Medicine, 2014
TRAP (Twin Reversed Arterial Perfusion) sequence is a rare syndrome seen in monochorionic twin pregnancies. It occurs in 1% of monochorionic twin pregnancies. It is characterized with a recipient fetus exhibiting lethal anomalies including acardia and a
Sümeyra Nergiz, Selda Demircan Sezer, Sündüz Özlem Altınkaya, Mert Küçük, Alparslan Ünsal, Ali Rıza Odabaşı, Hasan Yüksel   +6 more
doaj  

Complications in monochorionic twin pregnancies

Journal of Perinatal Medicine
Monochorionic placentas occur in two-thirds of identical (monozygotic) twin pregnancies and typically feature inter-fetal vascular anastomoses on their surface.
Klaritsch Philipp
doaj   +1 more source

A critical reappraisal of the carotid sinus and carotid bulb: Distinguishing neurohistological function from vascular geometry

The Anatomical Record, EarlyView.
This review redefines the carotid bulb (CB) as a variable geometric dilation shaped by hemodynamics and the carotid sinus (CS) as a conserved neurohistological baroreceptor field. Distinguishing these entities clarifies a century of anatomical confusion and links geometry, neurohistology, and clinical interpretation within a unified framework ...
Răzvan Costin Tudose, Nicolae Radu, Mugurel Constantin Rusu   +2 more
wiley   +1 more source

Prenatal identification of twin reversed arterial perfusion syndrome in the first trimester

, 1989
A twin pregnancy in which a single fetal death was diagnosed in the first trimester is described. Continued growth of the nonviable twin suggested the occurrence of the twin reversed arterial perfusion ...
Stiller, R J, Hobbins, J C, Romero, R, Pace, S   +3 more
core   +1 more source

Dissecting the dissection laboratory: Elements for designing a human anatomy laboratory

Anatomical Sciences Education, EarlyView.
Abstract The human anatomy dissection laboratory is a critical component of anatomical and medical education. Development, maintenance, and stocking of these laboratory spaces have unique demands, with all of the challenges in running a laboratory with Biosafety Laboratory Level 2 (BSL‐2) classification, housing a large volume of tissues saturated with
Rhiannon E. Robinson, Abbey Breckling, Danielle N. Edwards, Nicole Geske, Burhan Gharaibeh, Bobbie J. Leeper, Molly Ostwald, Mary Schilling, Bridgett Severt, Kelsey Stevens, J. P. Swigart, Jonathan J. Wisco, Melissa Zolnierz, Jeremy J. Grachan   +13 more
wiley   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

A rare case report of twin reversed arterial perfusion sequence in monochorionic diamniotic twin and outcome of Dr. Pump and Mr. Acardiac acephalus in a tertiary care centre [PDF]

Twin reversed arterial perfusion (TRAP) sequence or Acardiac twinning is a rare complication seen in monozygotic gestation. The reported incidence of Acardiac twin is 1 in 35000 births and 1 in 100 monozygotic twin gestation.
Thirupathi, Kalaivani, M. Meganathan, Jayalakshmi   +1 more
core   +1 more source

Engineered immunostimulatory H2O2‐producing microreactors driven by yeast as localized living cancer therapeutics

BMEMat, EarlyView.
Engineered yeast microreactors that produce H2O2 within tumors enable selective cancer cell killing while releasing immunostimulatory components, effectively suppressing local tumor growth and activating systemic antitumor immunity, with further efficacy enhanced by anti‐PD‐1 therapy and transarterial embolization.
Wenqian He, Chunjie Wang, Minming Chen, Weihao Yang, Bin Yu, Yuhang Hu, Hengze Ding, Yifan Yan, Zhijuan Yang, Liangzhu Feng   +9 more
wiley   +1 more source