Results 1 to 10 of about 524,795 (331)

Production of scaffold-free cell-based meat using cell sheet technology

npj Science of Food, 2022
In the production of cell-based meat, it is desirable to reduce animal-derived materials as much as possible to meet the challenges of sustainability.
Ryu-ichiro Tanaka, Katsuhisa Sakaguchi, Azumi Yoshida, Hironobu Takahashi, Yuji Haraguchi, Tatsuya Shimizu   +5 more
doaj   +1 more source

External pressure dynamics promote kidney viability and perfusate filtration during ex vivo kidney perfusion

Scientific Reports, 2022
Normothermic machine perfusion (NMP) has not yet been established as a technique for preserving organs for a day. A key contributing factor to the same is that the perfusing solutions cannot circulate continuously and evenly in the organs.
Yuhei Higashi, Jun Homma, Hidekazu Sekine, Hiroki Yago, Eiji Kobayashi, Tatsuya Shimizu   +5 more
doaj   +1 more source

Midnight/midday-synchronized expression of cryptochrome genes in the eyes of three teleost species, zebrafish, goldfish, and medaka

Zoological Letters, 2022
Photoperiodic responses are observed in many organisms living in the temperate zones. The circadian clock is involved in photoperiodic time measurement; however, the underlying molecular mechanism for detection of the day length remains unknown.
Marika Nakagawa, Keiko Okano, Yuya Saratani, Yosuke Shoji, Toshiyuki Okano   +4 more
doaj   +1 more source

Bioartificial pulsatile cuffs fabricated from human induced pluripotent stem cell-derived cardiomyocytes using a pre-vascularization technique

npj Regenerative Medicine, 2022
There is great interest in the development of techniques to bioengineer pulsatile myocardial tissue as a next-generation regenerative therapy for severe heart failure.
Yuki Endo, Jun Homma, Hidekazu Sekine, Katsuhisa Matsuura, Tatsuya Shimizu, Hiroshi Niinami   +5 more
doaj   +1 more source

Networked lymphatic endothelial cells in a transplanted cell sheet contribute to form functional lymphatic vessels

Scientific Reports, 2022
This study evaluated whether cell sheets containing a network of lymphatic endothelial cells (LECs) promoted lymphangiogenesis after transplantation in vivo.
Ayumi Inoue Nagahara, Jun Homma, Bikei Ryu, Hidekazu Sekine, Yuhei Higashi, Tatsuya Shimizu, Takakazu Kawamata   +6 more
doaj   +1 more source

In vitro ballooned hepatocytes can be produced by primary human hepatocytes and hepatic stellate cell sheets

Scientific Reports, 2022
Despite the increasing prevalence of Nonalcoholic steatohepatitis (NASH) worldwide, there is no effective treatment available for this disease. “Ballooned hepatocyte” is a characteristic finding in NASH and is correlated with disease prognosis, but their
Nobuhiro Hasui, Katsuhisa Sakaguchi, Tetsuya Ogawa, Yoshihiro Sakamoto, Tatsuya Shimizu   +4 more
doaj   +1 more source

The GGDEF protein Dgc2 suppresses both motility and biofilm formation in the filamentous cyanobacterium Leptolyngbya boryana

Microbiology Spectrum, 2023
Colony pattern formations of bacteria with motility manifest complicated morphological self-organization phenomena. Leptolyngbya boryana is a filamentous cyanobacterium, which has been used as a genetic model organism for studying metabolism including ...
Kazuma Toida, Wakana Kushida, Hiroki Yamamoto, Kyoka Yamamoto, Kaichi Ishii, Kazuma Uesaka, Robert A. Kanaly, Shinsuke Kutsuna, Kunio Ihara, Yuichi Fujita, Hideo Iwasaki   +10 more
doaj   +1 more source

Systematic Review of Fault Tolerant Techniques in Underwater Sensor Networks

Sensors, 2021
Sensor networks provide services to a broad range of applications ranging from intelligence service surveillance to weather forecasting. While most of the sensor networks are terrestrial, Underwater Sensor Networks (USN) are an emerging area.
Lauri Vihman, Maarja Kruusmaa, Jaan Raik
doaj   +1 more source

The composition of the gut microbiome differs among community dwelling older people with good and poor appetite

Journal of Cachexia, Sarcopenia and Muscle, 2021
Background Anorexia of ageing is common and important in the development of sarcopenia in older individuals. Links have been proposed between the gut microbiota and sarcopenia.
Natalie J. Cox, Ruth C.E. Bowyer, Mary Ni Lochlainn, Philippa M. Wells, Helen C. Roberts, Claire J. Steves   +5 more
doaj   +1 more source

The Mis6 inner kinetochore subcomplex maintains CENP-A nucleosomes against centromeric non-coding transcription during mitosis

Communications Biology, 2022
The kinetochore protein Mis6 (CENP-I) plays an important role in CENP-A maintenance during mitosis in fission yeast and blocks the indiscriminate transcription of non-coding RNAs at the core centromere to retain CENP-A during mitosis.
Hayato Hirai, Yuki Shogaki, Masamitsu Sato   +2 more
doaj   +1 more source