Results 101 to 110 of about 361,014 (259)
Ageing And Cancer As Diseases Of Epigenesis [PDF]
, 2009 Cancer and ageing are often said to be diseases of development. During the past fifty years, the genetic components of cancer and ageing have been intensely investigated since development, itself, was seen to be an epiphenomenon of the genome.
Gilbert, Scott F.
core +2 more sources
Identifying Causal Genotype–Phenotype Relationships for Population‐Sampled Parent–Child Trios
Genetic Epidemiology, Volume 50, Issue 1, February 2026.ABSTRACT The process by which genes are transmitted from parent to child provides a source of randomization preceding all other factors that may causally influence any particular child phenotype. Because of this, it is natural to consider genetic transmission as a source of experimental randomization.
Yushi Tang +2 more
wiley +1 more source
Genetic Epidemiology, Volume 50, Issue 1, February 2026.ABSTRACT A longstanding aim of developmental psychology and epidemiology is to understand the causal effects of parental phenotypes on offspring outcomes. Traditional approaches often fail to account for confounding and reverse causation. We evaluate the use of Mendelian randomisation with non‐inherited variants (MR‐NIV) to address these limitations ...
Benjamin Woolf +6 more
wiley +1 more source
Molecular Therapy: Nucleic Acids, 2019 Autism spectrum disorder (ASD) presents a set of childhood neurodevelopmental disorders with impairments in social communication and restricted, repetitive, and stereotyped patterns of behavior.
Yan Huang +10 more
doaj +1 more source
Does early life health predict schooling within twin pairs? [PDF]
, 2011 A large number of studies in labor economics estimate the returns to schooling using data on monozygotic twins, under the assumption that educational attainment is random within twin pairs. This exogeneity assumption has been commonly questioned, however,
Lundborg, Petter +2 more
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A Systematic Evaluation of the Performance of Multiple Brain Age Algorithms in Two Cohorts of Youth
Human Brain Mapping, Volume 47, Issue 2, 01 February 2026.Performance of five influential brain age estimation algorithms in two population‐based cohorts of youth. Brain age was quantified using estimates of brain structure, and performance was evaluated based on correlations with chronological age, error indices, sensitivity to demographic characteristics, scanning parameters, genetic similarity, and ...
Cleanthis Michael +8 more
wiley +1 more source
Earnings Mobility and Origin Dependence: What can twins say together with nonparametric econometrics? [PDF]
This study focuses on earnings immobility and its relation to the originin terms of both the social background and the initial position in the earnings distribution. Twin data is used to reveal the importance for the common background for immobility.
Nilsson, William
core +1 more source
Strikingly higher frequency in centenarians and twins of mtDNA mutation causing remodeling of replication origin in leukocytes [PDF]
, 2003 The presence of a genetic component in longevity is well known. Here, the association of a mtDNA mutation with a prolonged life span in humans was investigated.
Asin-Cayuela, Jordi +9 more
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Translational Psychiatry, 2011 Bipolar disorder (BD) is a severe mental disorder characterized by recurrent episodes of mania and depression. Serotonin transporter (HTT) is a target of antidepressants and is one of the strongest candidate molecules of mood disorder, however, genetic ...
H. Sugawara +12 more
semanticscholar +1 more source
Obesity, Volume 34, Issue 2, Page 394-406, February 2026.ABSTRACT Objective We investigated the impact of sex on the subcutaneous adipose tissue (AT) transcriptome and its obesity‐related adaptations. Methods We studied rare BMI‐discordant monozygotic twin pairs (ΔBMI > 2.5 kg/m2; 21 female, 16 male pairs) to assess how sex affects AT and whole‐body metabolism.
Hanna Haltia +12 more
wiley +1 more source