Results 101 to 110 of about 23,828 (193)

The Changing Epidemiology of Type 1 Diabetes: A Global Perspective

open access: yesDiabetes, Obesity and Metabolism, Volume 27, Issue S6, Page 3-14, August 2025.
Abstract The prevalence of type 1 diabetes is increasing, with significant implications for public health systems worldwide. This review provides a global overview of the current epidemiology of type 1 diabetes, examining the trends, risk factors, and regional variations in incidence.
Kirstine J. Bell, Samantha J. Lain
wiley   +1 more source

Bridging the gap in obesity research: A consensus statement from the European Society for Clinical Investigation

open access: yesEuropean Journal of Clinical Investigation, Volume 55, Issue 8, August 2025.
This consensus highlights critical research gaps in obesity epidemiology, phenotypic heterogeneity and clinical management, calling for advanced methodologies, collaborative strategies and innovative policies to mitigate the global obesity epidemic and its socio‐economic impacts.
Federico Carbone   +28 more
wiley   +1 more source

Heritability of sleep architecture based on home polysomnography

open access: yesJournal of Sleep Research, Volume 34, Issue 4, August 2025.
Summary We aimed to establish the heritability of polysomnography measures through the analysis of home polysomnography recordings from 648 participants in the Baependi Heart Study, a rural, family‐based, genetically admixed cohort based in the southeast of Brazil.
Mario Leocadio‐Miguel   +7 more
wiley   +1 more source

Redefining the Immunobiology of Organ Transplantation for New Clinical Horizons

open access: yesScandinavian Journal of Immunology, Volume 102, Issue 2, August 2025.
ABSTRACT Traditional organ transplantation relies on the Self–Non‐self (SNS) model of immunity, focusing on donor–recipient compatibility and aggressive immunosuppression to prevent acute rejection. Although effective early, this strategy does not prevent chronic rejection and cannot account for operational tolerance, failure of perfectly HLA‐matched ...
Masoud H. Manjili
wiley   +1 more source

Updated insights into the molecular pathogenesis of canine atopic dermatitis

open access: yesVeterinary Dermatology, Volume 36, Issue 4, Page 375-384, August 2025.
Abstract Atopic dermatitis (AD) is a common and chronic inflammatory skin disease with frequent relapses. The genomics revolution has greatly contributed and revolutionised our knowledge of human AD; understanding the molecular skin fingerprint of AD and associated pathogenic immune pathways has led to preclinical assessments of several novel ...
Frane Banovic
wiley   +1 more source

Identifying Genomic Variations in Monozygotic Twins Discordant for Autism Spectrum Disorder Using Whole-Genome Sequencing

open access: yesMolecular Therapy: Nucleic Acids, 2019
Autism spectrum disorder (ASD) presents a set of childhood neurodevelopmental disorders with impairments in social communication and restricted, repetitive, and stereotyped patterns of behavior.
Yan Huang   +10 more
doaj  

COULD RAPIDLY MUTATING Y-STRS BE A POTENTIAL FORENSIC TOOL IN DISCRIMINATING LEBANESE MONOZYGOTIC TWINS?

open access: yesGenetics & Applications, 2018
Despite the high power of discrimination that characterizes the well identified 16 to 24 autosomal short tandem repeat markers, monozygotic twins differentiation is generally limited.
Paula Romanos, Jamilah Borjac
doaj  

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