Results 101 to 110 of about 753,593 (350)

Digital twins to personalize medicine

Genome Medicine, 2019
Personalized medicine requires the integration and processing of vast amounts of data. Here, we propose a solution to this challenge that is based on constructing Digital Twins.
B. Björnsson, C. Borrebaeck, Nils Elander, T. Gasslander, D. Gawel, M. Gustafsson, Rebecka Jörnsten, Eunjung Lee, Xinxiu Li, S. Lilja, D. Martínez-Enguita, A. Matussek, P. Sandström, Samuel Schäfer, Margaretha Stenmarker, Xiao-Feng Sun, O. Sysoev, Huan Zhang, M. Benson   +18 more
semanticscholar   +1 more source

The Role of Invasive Procedures in the Treatment of Complicated Gastrointestinal Graft‐Versus‐Host Disease in Pediatric Patients

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Gastrointestinal graft‐versus‐host disease (GI GVHD) following hematopoietic stem cell transplant is typically managed with medical therapy, but surgery and angioembolization may be warranted in selected cases with life‐threatening complications.
Gaia Brunetti, Giorgio Persano, Chiara Grimaldi, Pier Luigi Di Paolo, Carmen Malaspina, Francesco Quagliarella, Valerio Balassone, Anna Chiara Iolanda Contini, Gian Luigi Natali, Rita Alaggio, Ivan Pietro Aloi, Tamara Caldaro, Alessandro Crocoli   +12 more
wiley   +1 more source

Ovarian reserve and anti-Mullerian hormone (AMH) in mothers of dizygotic twins [PDF]

, 2013
This study aimed to explore if natural dizygotic (DZ) twinning is associated with earlier menopause and lower anti-Mullerian hormone (AMH) values. We investigated if advanced biological reproductive aging, which can be responsible for the multiple ...
Boomsma, Dorret I, Konig, Tamar E, Lambalk, Cornelis, Van der Stroom, Elizabeth MC, Vink, Jacqueline M   +4 more
core   +4 more sources

A Feature-Based Framework for Structuring Industrial Digital Twins

IEEE Access, 2020
Digital twin is a virtual entity that is linked to a real-world entity. Both the link and the virtual representation can be realized in several different ways.
Juuso Autiosalo, Jari Vepsäläinen, R. Viitala, K. Tammi   +3 more
semanticscholar   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Non-linear and switchable light preferences of nocturnal loach (Misgurnus anguillicaudatus)

Scientific Reports
Light conditions have substantial effects on living organisms through a variety of aspects of individual life, such as survival, feeding, reproduction, stress responses, and behavioral rhythms.
Yuki Yoshikawa, Keiko Okano, Toshiyuki Okano   +2 more
doaj   +1 more source

The relationship between Hippocampal asymmetry and working memory processing in combat-related PTSD: a monozygotic twin study [PDF]

, 2012
BACKGROUND: PTSD is associated with reduction in hippocampal volume and abnormalities in hippocampal function. Hippocampal asymmetry has received less attention, but potentially could indicate lateralised differences in vulnerability to trauma.
Clark, C., Galletly, C., Gilbertson, M., Hall, T., McFarlane, A., Metzger, L., Orr, S., Pitman, R., Veltmeyer, M.   +8 more
core   +2 more sources

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

A serum-free culture medium production system by co-culture combining growth factor-secreting cells and l-lactate-assimilating cyanobacteria for sustainable cultured meat production

Scientific Reports
Large-scale production of cultured meat requires bulk culture medium containing growth-promoting proteins from animal serum. However, animal serum for mammalian cell culture is associated with high costs, ethical concerns, and contamination risks.
Shanga Chu, Yuji Haraguchi, Toru Asahi, Yuichi Kato, Akihiko Kondo, Tomohisa Hasunuma, Tatsuya Shimizu   +6 more
doaj   +1 more source

An investigation into the voice of identical twins [PDF]

, 2013
An investigation into the voice of identical twinsRunning title:  Voice of identical twinsAbstractThe study aimed at perceptually and acoustically differentiating the voices of identical twins from each other.
Sebastian, Swapna
core   +1 more source