Results 201 to 210 of about 524,795 (331)

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source

A Technological Review of Digital Twins and Artificial Intelligence for Personalized and Predictive Healthcare. [PDF]

Healthcare (Basel)
Chaparro-Cárdenas SL, Ramirez-Bautista JA, Terven J, Córdova-Esparza DM, Romero-Gonzalez JA, Ramírez-Pedraza A, Chavez-Urbiola EA.   +6 more
europepmc   +1 more source

On the Theory of Twinned Space Groups

, 1959
R. Sadanaga
openalex   +2 more sources

Comments on the Analysis of Twin Samples—II. The Sample [PDF]

, 1958
Gordon Allen
openalex   +1 more source

Twins twin transfusion syndrome in monochorionic twins [PDF]

International Journal of Pregnancy & Child Birth, 2019
Orcid https: Mohamed W Gawish, AAAl Ibrahim, S Al-Obaidli   +2 more
openaire   +2 more sources

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

Molecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim   +18 more
wiley   +1 more source

Woman with term presentation of acaridac twin pregnancy with three cesarean section scars: a case report. [PDF]

J Med Case Rep
Dinsa LH, Hailu AM, Eticha AD.
europepmc   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

The geo-politics of resilience: On the historical convergence between ecology, artificial intelligence, and corporate strategy. [PDF]

New Media Soc
Halpern O.
europepmc   +1 more source

Muscular Dystrophy in Three Pairs of Twins [PDF]

, 1959
Hubert C. Soltan
openalex   +1 more source