Results 281 to 290 of about 524,795 (331)

The role of circular RNAs in regulating cytokine signaling in cancer

FEBS Open Bio, EarlyView.
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi, Swati, Amit Mishra, Amaresh Panda, Vivek Sharma   +4 more
wiley   +1 more source

Familial risks of five types of osteoarthritis in first-, second- and third-degree relatives - A nationwide Swedish family study. [PDF]

Osteoarthr Cartil Open
Anker-Hansen C, Pirouzifard M, Sundquist J, Sundquist K, Zöller B.   +4 more
europepmc   +1 more source

Identifying prognostic targets in metastatic prostate cancer beyond AR

FEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng, Eric Feng, Tracy Berg, Isabella S. Nguyen, Lilac G. Nguyen, William Chen, Meng Zhang, David Quigley, Marina Sharifi, Haolong Li, Ilsa Coleman, Peter S. Nelson, Martin Sjöström, Shuang G. Zhao   +13 more
wiley   +1 more source

Emergency neurosurgical separation of pygopagus conjoined twins in a triplet pregnancy: illustrative case. [PDF]

J Neurosurg Case Lessons
Ali EH, Abebe YN, Haile MG, Bayable A.
europepmc   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

Outcome of monochorionic diamniotic twin pregnancy with selective fetal growth restriction and continuous or intermittent absent or reversed end-diastolic umbilical artery flow: international multicenter cohort study. [PDF]

Ultrasound Obstet Gynecol
Noll ATR, van Hoogstraten A, Nulens K, van Geloven N, Van Mieghem T, Shinar S, Zuazagoitia PA, Bennasar M, Russo FM, Tiblad E, Herling L, Lewi L, Joanne Verweij EJT, ALIGN Study Group.   +13 more
europepmc   +1 more source

Earthing effects on mitochondrial function: ATP production and ROS generation

FEBS Open Bio, EarlyView.
In contrast to sham and naive controls, grounded mitochondria not only exhibit significantly enhanced energy production but also demonstrate a remarkable reduction in membrane potential and oxidative stress. This suggests a profound improvement in mitochondrial health, presenting a promising avenue for therapeutic interventions.
Cecilia Giulivi, Richard Kotz
wiley   +1 more source

The deep winding at the brain surface: replicating a historical report associating the 'bridged' central sulcus with the pli de passage fronto-pariétal moyen. [PDF]

Brain Struct Funct
Schweizer R, Muellen AM, Stropel J.
europepmc   +1 more source

Biophysical characterization and ion transport with cell‐based and proteoliposome reconstitution assays of invertebrate K+‐Cl− cotransporters

FEBS Open Bio, EarlyView.
The K+‐Cl− cotransporters (KCCs) facilitate the symport of ions across the plasma membrane. They participate in physiological processes including neuronal regulation. Here, we characterized KCCs from Drosophila and Hydra vulgaris. Comparative analyses of transporters provide insights into the mechanism of KCC ion transport, regulation, and evolution ...
Satoshi Fudo, Marina Verkhovskaya, Coralie Di Scala, Claudio Rivera, Tommi Kajander   +4 more
wiley   +1 more source

Individualized intervention and growth dynamics assessment in TRAP sequence with conjoined twins based on radiofrequency ablation. [PDF]

BMC Pregnancy Childbirth
Lai H, Zhu H, Zhang J, Xiao J, Liu M, Liu D, Li Z, Zhou X.   +7 more
europepmc   +1 more source