Results 101 to 110 of about 135,103 (314)
Angewandte Chemie International Edition, Accepted Article.DNA four‐way junctions (4WJs) play an important biological role in DNA repair and recombination, and viral regulation, and are attractive therapeutic targets. Compounds that recognise the junction structure are rare; in this work, we describe cationic metallo‐supramolecular M2L4 cages as a new type of 4WJ binder with nanomolar affinities. A combination
Samuel J. Dettmer +6 more
wiley +1 more source
Functional Ambidexterity of an Ancient Nucleic Acid‐Binding Domain
Angewandte Chemie International Edition, Accepted Article.The helix‐hairpin‐helix (HhH) motif is an ancient and ubiquitous nucleic acid‐binding element that has emerged as a model system for studying the evolution of dsDNA‐binding domains from simple peptides that phase separate with RNA. We analyzed the entire putative evolutionary trajectory of the HhH motif – from a flexible peptide to a folded domain ...
Liam Longo +8 more
wiley +1 more source
A Phosphine‐ß‐diketiminate Nickel(I)‐Complex for Small Molecule Activation
ChemPlusChem, Volume 87, Issue 12, December 2022., 2022 A phosphine‐ß‐diketiminate Ni(I)‐complex uses the reductive potential of Ni(I) to enable the activation of small molecules with different substrate classes, such as CH2X2 (X=Br, I), I2 or Ph2E2 (E=S, Se). The ligand's design allows a stabilization of the reactive Ni(I) species while at the same time enabling activation processes due to a hemilabile ...
Christina Zovko +5 more
wiley +1 more source
Angewandte Chemie International Edition, Accepted Article.Polyelemental nanoparticles (PE NPs), those consisting of four or more elements, exhibit unique properties from synergistic compositional effects. Examples include high entropy alloys, high entropy intermetallics, and multiphase types, including Janus and core‐shell architectures.
Nabojit Kar +4 more
wiley +1 more source
PhishAri: Automatic Realtime Phishing Detection on Twitter [PDF]
arXiv, 2013 With the advent of online social media, phishers have started using social networks like Twitter, Facebook, and Foursquare to spread phishing scams. Twitter is an immensely popular micro-blogging network where people post short messages of 140 characters called tweets.
arxiv
Angewandte Chemie International Edition, Accepted Article.The synthesis of polarized N‐heterocyclic olefins (NHOs) based on an imidazo[1,5‐a]pyridine scaffold is presented. In contrast to regular NHOs the unique bicyclic heterocyclic core allows the incorporation of various substituents in close proximity to the highly polarized exocyclic C–C bond.
Robin Esken +6 more
wiley +1 more source
Understanding Types of Users on Twitter [PDF]
arXiv, 2014 People use microblogging platforms like Twitter to involve with other users for a wide range of interests and practices. Twitter profiles run by different types of users such as humans, bots, spammers, businesses and professionals. This research work identifies six broad classes of Twitter users, and employs a supervised machine learning approach which
arxiv
When Follow is Just One Click Away: Understanding Twitter Follow Behavior in the 2016 U.S. Presidential Election [PDF]
arXiv, 2017 Motivated by the two paradoxical facts that the marginal cost of following one extra candidate is close to zero and that the majority of Twitter users choose to follow only one or two candidates, we study the Twitter follow behaviors observed in the 2016 U.S. presidential election.
arxiv
Survey sabotage: Insights into reducing the risk of fraudulent responses in online surveys
Anatomical Sciences Education, EarlyView.Abstract Validity is a key element of many forms of research—particularly surveys, which are often used in health professions education research. A survey must accurately measure what it is intended to measure to be considered valid. This is becoming increasingly difficult in the age of artificial intelligence (AI), where “bots” (short for robots) are ...
James Bonnamy +3 more
wiley +1 more source