Results 111 to 120 of about 15,180,548 (316)
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Synthesis, crystal structure and properties of YB2C2
Journal of Asian Ceramic SocietiesYB2C2 is a novel ultra-high temperature ceramic material with high damage tolerance. In this work, the synthesis mechanism, crystal structure, electronic structure, elastic properties and thermal shock resistance of YB2C2 were systematically investigated
Yueming Li +5 more
doaj +1 more source
Two-dimensional DCT/IDCT architecture [PDF]
, 2003 A fully parallel architecture for the computation of a two-dimensional (2-D) discrete cosine transform (DCT), based on row-column decomposition is presented.
Jollah, I, Aggoun, A
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
A Lower Bound on the Number of Parity-Check Bits of Multiple-Cluster-Error Correcting Two-Dimensional Linear Codes [PDF]
, 2008 P(論文)Recently, two-dimensional or three-dimensional error correction coding schemes have been widely studied in the context of optical recording applications such as page-oriented optical memories and volume holographic storage.
MIZUKAMI, Ken-ichi +5 more
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Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
The Two-Dimensional, Rectangular, Guillotineable-Layout Cutting Problem with a Single Defect [PDF]
In this paper, a two-dimensional cutting problem is considered in which a single plate (large object) has to be cut down into a set of small items of maximal value.
Marcos N. Arenales +3 more
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An overview on warranty cost modelling in two-dimensional warranty using neuro-fuzzy approach [PDF]
, 2012 In early study of manufacturing, warranty studies were mainly carried out by researchers in the legal profession and, thus, such articles appeared only in the law journals. Subsequently, warranty studies attracted researchers from such field as economics,
Nur Izzati Binti Jamahir +5 more
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Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Closed, Two Dimensional Surface Dynamics
Frontiers in Physics, 2018 We present dynamic equations for two dimensional closed surfaces and analytically solve it for some simplified cases. We derive final equations for surface normal motions by two different ways. The solution of the equations of motions in normal direction
David V. Svintradze
doaj +1 more source