Results 171 to 180 of about 19,563,565 (291)

A Specific tRNA Half, 3'tiRNA‐GlyGCC, Regulates Hypoxic Pulmonary Artery Smooth Muscle Cell Proliferation via Myrf‐Mediated Endoplasmic Reticulum Stress

Cell Proliferation, EarlyView.
A schematic diagram illustrating how 3′tiRNA‐GlyGCC promotes the endoplasmic reticulum stress (ERS) and proliferation in hypoxic pulmonary artery smooth muscle cells (PASMCs) by inhibiting the expression of myelin regulatory factor (Myrf), ultimately leading to pulmonary hypertension (PH).
Lixin Zhang, Xiaoyu Guan, Xiangrui Zhu, Yingying Hao, Ya Xu, Hao Yuan, Danni Gao, Hongxia Du, Jiayu Li, Weiwei Cao, Cui Ma, Xiaoying Wang   +11 more
wiley   +1 more source

Chd4 and ThPOK cooperate to preserve structural and electrophysiological integrity of the adult heart through Sprr1a repression

The FEBS Journal, EarlyView.
Chd4/NuRD and ThPOK cooperate to maintain transcriptional repression and nuclear organization in adult cardiomyocytes. Chd4 loss reduces miR‐150‐5p, relieving repression of Sprr1a, while ThPOK loss further enhances Sprr1a activation, possibly through altered chromatin–lamina interactions.
Fadoua El Abdellaoui‐Soussi, Apolonia Novillo, Rocío Brea, Marta Ysbert, Lorena Cussó, Gonzalo Pizarro‐Sánchez, Manuel Desco, Iván Hernández, Ángel Luis Armesilla, Ignacio Pérez de Castro, Alicia R. Folgueras, Juan Miguel Redondo, Pablo Gómez‐del Arco   +12 more
wiley   +1 more source

Tenapanor Beyond Phosphate: Gut Sodium Transport, Stool Transit Time, and Volume Balance in Dialysis Patients

Hemodialysis International, EarlyView.
ABSTRACT Introduction Tenapanor, a minimally absorbed intestinal NHE3 inhibitor approved for hyperphosphatemia in dialysis, lowers phosphate and reduces intestinal sodium absorption. Its sodium–water signal may have implications beyond phosphate but remains poorly separated from diarrhea‐mediated losses and dialysis prescription artifacts. Methods This
Lucas Maciel de Almeida Corrêa, Luiggi Kevin Virgino Brandão, Clara Belo Gamon Santiago, Alexandre de Assis Barbosa, Gabriel Rian Mazur, Gabriel Costa de Santana, Yan Roberth Delmiro Silva, Letícia Esteves Dante, Ivan Felipe Dutra Júnior   +8 more
wiley   +1 more source

Multimodality registration of two-dimensional echocardiography and cardiac CT for mitral valve diagnosis and surgical planning. [PDF]

J Med Imaging (Bellingham), 2017
Khalil A, Faisal A, Ng SC, Liew YM, Lai KW.   +4 more
europepmc   +1 more source

Two-Dimensional Echocardiography

Japanese Journal of Medical Ultrasound Technology, 1991
openaire   +1 more source

Catheter Ablation: Evolution and Efficiencies

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT The present review includes a discussion the goals and pitfalls of efficiency in the medical profession, a historical perspective on the evolution of catheter ablation in the field of electrophysiology (EP), and the data regarding the relationship between efficiency and outcomes in the EP lab. Focus on efficacy is critical to maximize resource
Aravind G. Kalluri, Bradley P. Knight
wiley   +1 more source

Clinical Utility of Tissue Proximity Indication With a Variable‐Loop Circular Catheter for Pulmonary Vein Isolation

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background The variable‐loop circular catheter (VLCC, VARIPULSE) is a pulsed‐field ablation (PFA) catheter equipped with a Tissue Proximity Indication (TPI) function, which monitors catheter‐tissue contact. Although TPI‐negative sites have been reported to contribute to gap formation, no studies have evaluated the utility of real‐time function.
Masataka Narita, Daisuke Kawano, Naomichi Tanaka, Tsukasa Naganuma, Wataru Sasaki, Kazuhisa Matsumoto, Kei Matsumoto, Hitoshi Mori, Yoshifumi Ikeda, Ritsushi Kato   +9 more
wiley   +1 more source

Refining Residual Ischemic Stroke Risk in Anticoagulated Atrial Fibrillation Using Index Outpatient LA Diameter: The CHA2DS2‐VALa Score

Journal of Cardiovascular Electrophysiology, EarlyView.
In anticoagulated atrial fibrillation, residual ischemic stroke risk persists despite guideline‐directed therapy. In this single‐center cohort, an enlarged index outpatient left atrial diameter independently predicted stroke and improved risk stratification when added to CHA2DS2‐VA (CHA2DS2‐VALa), supporting a simple, clinically implementable ...
Sefa Erdi Ömür, Emin Koyun, Gülşen Genç Tapar, Kayıhan Karaman, Metin Karayakali, Ataç Çelik, Uğur Kulu, Yasin Taşkin   +7 more
wiley   +1 more source

Large Language Model‐Based Localization of Premature Ventricular Contraction Origins: A Retrospective Diagnostic Accuracy Study

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background Accurate localization of premature ventricular contraction (PVC) origin from 12‐lead electrocardiography (ECG) is important for procedural planning in catheter ablation. Although convolutional neural network (CNN)‐based models have shown promising diagnostic performance, they require task‐specific training and remain limited in ...
Kazuhisa Matsumoto, Yuya Fujisaki, Syunta Higuchi, Masataka Narita, Wataru Sasaki, Tsukasa Naganuma, Naomichi Tanaka, Daisuke Kawano, Kei Matsumoto, Wataru Yoshino, Yoshifumi Ikeda, Ritsushi Kato, Hitoshi Mori   +12 more
wiley   +1 more source

Fact or Artifact in Two-Dimensional Echocardiography: Avoiding Misdiagnosis and Missed Diagnosis. [PDF]

J Am Soc Echocardiogr, 2016
Bertrand PB, Levine RA, Isselbacher EM, Vandervoort PM.   +3 more
europepmc   +1 more source