Results 201 to 210 of about 68,414 (306)

Sex differences in cerebral blood flow and cardiac function in response to exercise in the heat

Experimental Physiology, EarlyView.
Abstract We investigated the effect of exercising in hot conditions on cerebral blood flow and systolic left ventricular (LV) function in males and females, to explore sex differences. The experimental condition consisted of walking on a treadmill at 5 km/h and 2% incline, inside a heat chamber at 40°C (50% relative humidity), for 90 min.
João Carlos Locatelli, Juliene G. Costa, Kristanti W. Wigati, Jesse L. Criddle, Julie J. Collis, Xingwei Xu, Louise H. Naylor, Howard H. Carter, Shane K. Maloney, Robert A. McLaughlin, Andrew Haynes, Helen Jones, Keith George, Daniel J. Green   +13 more
wiley   +1 more source

Effects of high‐intensity interval training on cardiac function in hypertensive and normotensive men: Effects of antihypertensive treatment

Experimental Physiology, Volume 111, Issue 6, Page 2945-2955, 1 June 2026.
Abstract Exercise training is recommended for individuals with hypertension because it has been shown to lower blood pressure and reverse left ventricular concentric remodelling and mass. However, it is unclear how hypertensive individuals respond in comparison to normotensive individuals and to what extent medical treatment affects the outcome of ...
Mads Fischer, Jon Egelund, Matteo Fiorenza, Thomas S. Ehlers, Michael Nyberg, Jesper J. Linde, Lasse Gliemann, Thomas P. Gunnarsson, Jens Bangsbo   +8 more
wiley   +1 more source

Identification of the individual cardiac contraction threshold during high‐frame‐rate stress echocardiography

Experimental Physiology, EarlyView.
Abstract The clinical assessment of cardiovascular function during exercise using stress echocardiography is essential for accurate cardiac diagnosis. However, normal limitations of cardiac deformation responses to increasing physical exertion remain poorly understood.
Fabian Spahiu, Max Hagemann, Michelle Ottlik, Moritz Lampkemeyer, Eric J. Stöhr   +4 more
wiley   +1 more source

Advances in cardiac devices and bioelectronics augmented with artificial intelligence

The Journal of Physiology, EarlyView.
Abstract figure legend Interfaces between the human heart, diagnostic bioelectronics, artificial intelligence, and clinical care. From left to right: Human heart and biosensor interface; representative waveforms of common diagnostic bioelectronic sensing modalities.
Charles Stark, Eric Rytkin, Andrei Alexandru Mircea, Igor R. Efimov   +3 more
wiley   +1 more source

Cardiac remodelling in type 2 diabetes: Pathophysiological mechanisms and opportunities for multiscale computational modelling and simulation

The Journal of Physiology, EarlyView.
Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand, Jakub Tomek, Blanca Rodriguez   +2 more
wiley   +1 more source

Mitral leaflet separation index. An easy two dimensional echocardiography technique for assessment of mitral valve area before and after percutaneous balloon mitral valvuloplasty. [PDF]

Egypt Heart J, 2018
Raafat SS, Ramzy AA, El-Hadidy AF, Abd Allah MA, Hanna HF.   +4 more
europepmc   +1 more source

Enhancing stroke risk stratification in atrial fibrillation through non‐Newtonian blood modelling and Gaussian process emulation

The Journal of Physiology, EarlyView.
Abstract figure legend Non‐Newtonian modelling and GPEs for stroke risk in atrial fibrilation patients. Abstract Atrial fibrillation (AF) is the most common heart arrhythmia, linked to a five‐fold increase in stroke risk. The left atrial appendage (LAA), prone to blood stasis, is a common thrombus formation site in AF patients.
Paolo Melidoro, Abdel Rahman Amr Sultan, Ahmed Qureshi, Magdi H. Yacoub, Khalil L. Elkhodary, Gregory Y. H. Lip, Natalie Montarello, Nishant Lahoti, Ronak Rajani, Magdalena Klis, Steven E. Williams, Oleg Aslanidi, Adelaide De Vecchi   +12 more
wiley   +1 more source

Angiotensin‐converting enzyme and exercise adaptations: Genetic variability, pharmacological modulation and future directions

The Journal of Physiology, EarlyView.
Abstract figure legend ACE I/D genotype, enzyme activity and integrated physiological adaptations. Upper panel: Conceptual framework linking the ACE I/D polymorphism (left) with circulating/tissue ACE activity (centre; violin plots based on hypothetical data for illustration) and strength/power versus endurance phenotypes (right).
Tórur Sjúrðarson, Nikolai B. Nordsborg   +1 more
wiley   +1 more source

Volumetric and Functional Features of Left Atrium in Chronic Schizophrenia-Detailed Analysis from Three-Dimensional Speckle-Tracking Echocardiographic MAGYAR-Path Study. [PDF]

Biomedicines
Nemes A, Halcsik R, Kormányos Á, Gyenes N, Keifari A, Lázár BA, Lengyel C, Kálmán J.   +7 more
europepmc   +1 more source

Ro5‐4864, a ligand of the mitochondrial translocator protein, protects against heart failure in mice via regulation of the p62‐Keap1‐Nrf2 axis

The Journal of Physiology, EarlyView.
Abstract figure legend Graphical abstract of the proposed Ro5‐4864 mechanism of action via p62‐Keap1‐Nrf2 axis in heart failure. TSPO, the 18‐kDa mitochondrial translocator protein of the outer mitochondrial membrane, can directly interact with p62 (also known as SQSTM1), which is crucial for the degradation of damaged mitochondria by autophagy ...
Daphne A. Diloretto, Phung N. Thai, Gabriela Grigorean, Veneese J. Brown, Tjien Dwyer, Nipavan Chiamvimonvat, Elena N. Dedkova, Saul Schaefer   +7 more
wiley   +1 more source