Results 121 to 130 of about 24,124,459 (297)

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Anomalous twin boundaries in two dimensional materials

Nature Communications, 2018
All materials subjected to mechanical deformation form low energy interfaces known as twin boundaries. Here, the authors investigate a variety of structural features that form upon bending atomically thin 2D-crystals, and predict distinct classes of post
A. P. Rooney, Z. Li, W. Zhao, A. Gholinia, A. Kozikov, G. Auton, F. Ding, R. V. Gorbachev, R. J. Young, S. J. Haigh   +9 more
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Fabrication of two-dimensional polymers and two-dimensional materials

, 2016
Die vorliegende Arbeit beinhaltet drei unterschiedliche Ansätze zur Herstellung neuer zweidimensionaler Polymere bzw. zweidimensionaler Materialien. Im ersten Teil werden zwei verschiedene Methoden zur nichtkovalenten Assemblierung beschrieben zur Herstellung groß-flächiger Einzelmoleküllagen.
openaire   +4 more sources

MXene-MoS2 engineered heterostructured vertical memristors array: high-performance non-volatile memory with scalable integration

npj 2D Materials and Applications
The emergence of artificial intelligence and neuromorphic computing has revealed the importance of two-dimensional (2D) layered materials in the field of non-volatile memory technologies.
Kubra Sattar, Ivan S. Babichuk, Saleem Ayaz Khan, Jian Yang, Syed Rizwan   +4 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Generalizable growth of 2D twisted transition metal dichalcogenide heterostructures under non-equilibrium thermodynamic conditions

Nature Communications
Twisted two-dimensional (2D) transition metal dichalcogenide (TMD) structures have emerged as a versatile platform for optoelectronics and quantum materials, but their controlled bottom-up synthesis remains challenging.
Qiuyin Qin, Xin Li, Wei Li, Wangpeng Chen, Shihao Zhang, Shula Chen, Ziyu Luo, Zhiwen Hua, Liqiang Zhang, Wenhao Xi, Wenjing Xie, Dingyi Shen, Bo Li, Yuan Liu, Jia Li, Ruixia Wu, Xidong Duan   +16 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Two dimensional superconductors in electrides

New Journal of Physics, 2017
Two-dimensional (2D) superconductors are always a research hotspot in superconductivity, due to the huge importance of 2D superconductors in quantum phenomena transitions.
Yanfeng Ge, Shan Guan, Yong Liu
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source