Results 91 to 100 of about 18,592,441 (198)

Improved models of roundabout lane capacity

open access: yes, 2014
Accurate roundabout capacity models are essential for optimising roundabout designs and minimising queues and delays, but there exists significant variation in the capacities predicted by different state-of-the-art models. This paper presents the results
Waterson, Ben   +2 more
core   +1 more source

USP25 stabilises GLI1 through K48‐linked deubiquitination within a reciprocal regulatory circuit in osteoarthritis models

open access: yesClinical and Translational Medicine, Volume 16, Issue 10, October 2026.
GLI1‐centred USP25‐GLI1 reciprocal regulation in OA‐relevant models. Hedgehog/GLI1 signalling transcriptionally reinforces USP25 expression, while USP25 deubiquitinates and stabilises GLI1. This reciprocal circuit is associated with inflammatory and cartilage‐catabolic changes in the tested models.
Qian Zhang   +4 more
wiley   +1 more source

Flower Roundabouts And Double-Lane Roundabouts: A Comparative Performance Analysis

open access: yesArchives of Civil Engineering, 2014
In the paper, a choice criterion between flower roundabouts and double-lane roundabouts is proposed, focusing on operational benefits that can derive from one scheme over the other, and outlining a general framework for benefit-cost analysis. In order to
Giuffrè O.   +4 more
doaj   +1 more source

The assembly of tetrameric human L‐lactate dehydrogenase is regulated by ionic strength, β‐NADH binding, cyclic peptides, and long‐chain dicarboxylates

open access: yesProtein Science, Volume 35, Issue 10, October 2026.
Abstract Lactate dehydrogenases catalyze the reduction of pyruvate to lactate, the generation of which is of importance for the energetic metabolism of malignant cells. In particular, human cancer cells overexpress lactate dehydrogenase A (hLDH‐A), whose catalytic activity depends on its assembly into the corresponding homotetramer (denoted as hLDH‐5),
Alessandra Stefan   +7 more
wiley   +1 more source

A RECONSTRUCTION OF THE TWO-LANE ROUNDABOUT IN VELENJE [PDF]

open access: yes, 2016
Krožno križišče je križišče krožne oblike, kjer promet poteka okoli sredinskega otoka v nasprotni smeri urinega kazalca. Prednosti krožnih križišč so, da so varnejša, umirjajo promet, imajo manj konfliktnih točk, pretok prometa je bolj učinkovit ...
Lešnik, Anže
core  

Traffic flow behavior at a single-lane urban roundabout

open access: yes, 2018
In this paper, we propose a stochastic cellular automata model to study the traffic behavior at a single-lane roundabout. Vehicles can enter the interior lane or exit from it via [Formula: see text] intersecting lane, the boundary conditions are ...
L. Cisneros-Villalobos   +4 more
core   +1 more source

The cold case of state transition 7 (stt7) mutants of Chlamydomonas reinhardtii, solved by whole‐genome sequencing

open access: yesNew Phytologist, Volume 252, Issue 1, Page 145-162, October 2026.
Long‐read whole‐genome sequencing revealed extensive chromosomal rearrangements and aneuploidy in a widely used Chlamydomonas reinhardtii stt7‐1 mutant. The STT7 gene (shown in red) was found to be split between two rearranged chromosomes, providing a molecular explanation for the long‐standing failure of this mutant in genetic crosses.
Sandrine Bujaldon   +3 more
wiley   +1 more source

Conflict Models for Single-Lane Roundabout Slip Lanes from Microsimulation

open access: yes, 2011
Conflict patterns at single-lane roundabouts with and without slip lanes were evaluated and compared through VISSIM, the microscopic simulation program for multimodal traffic flow modeling, and surrogate safety assessment model (SSAM) analysis.
Bastian J. Schroeder   +3 more
core   +1 more source

Improving Traffic Safety at Two-Lane Roundabouts Through Legal and Technical Regulatory Measures

open access: yesJTTTP - JOURNAL OF TRAFFIC AND TRANSPORT THEORY AND PRACTICE
The title of the paper reflects the traffic-related issues associated with two-lane roundabouts, from the perspective of the level of service and traffic safety. Particular focus is placed on establishing traffic rules in two-lane roundabouts and eliminating ambiguities regarding the right of way of vehicles when exiting the circulatory roadway.The ...
Danislav Drašković   +3 more
openaire   +1 more source

Proposal for the reconstruction of a two-lane roundabout with capacity and traffic-safety analysis [PDF]

open access: yes, 2018
Krožna križišča so križišča, kjer prednostna cesta poteka v zaključenem krogu, promet pa se odvija v nasprotni smeri gibanja urnih kazalcev. Razvila so se kot alternativa klasičnim križiščem in imajo številne prednosti.
Logar, Domen
core  

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