Results 111 to 120 of about 5,045,379 (328)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Entanglement evolution in a cascaded system with losses

, 2009
The dynamics of a cascaded system that consists of two atom-cavity subsystems is studied by using the quantum trajectory method. Unwanted losses are included, such as photon absorption and scattering by the cavity mirrors and spontaneous emission of the ...
Allahverdyan, Bell, Bell, Bose, Carmichael, Carmichael, Christian Di Fidio, Clark, Dalibard, Di Fidio, Di Fidio, Di Fidio, Duan, Duan, Dum, Einstein, Gardiner, Gu, Haroche, Nielsen, Parkins, Schrödinger, Werner Vogel, Wootters   +23 more
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Entangling two atoms via spontaneous emission

, 2003
We discuss the creation of entanglement between two two-level atoms in the dissipative process of spontaneous emission. It is shown that spontaneous emission can lead to a transient entanglement between the atoms even if the atoms were prepared initially
Ficek, Z., Tanas, R
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Non-Markovian Dynamics and Entanglement of Two-level Atoms in a Common Field

, 2011
We derive the stochastic equations and consider the non-Markovian dynamics of a system of multiple two-level atoms in a common quantum field. We make only the dipole approximation for the atoms and assume weak atom-field interactions.
Accardi L, Alicki R, Anastopoulos C Shresta S Hu B L, B L Hu, Breuer H P, Breuer H P, C H Fleming, Carmichael H J, Charis Anastopoulos, Cohen-Tannoudji C, Cunha M T, Fleming C H, Fleming C H Hu B L, Fleming C H Hu B L Roura A, Fleming C H Johnson P R Hu B L, Fleming C H Roura A Hu B L, Ingarden R S, Klimov A B, Milonni P W, N I Cummings, Scala M, Swain S, Walls D F, Weiss U, Yna M, Yna M, Yu T Eberly J H   +26 more
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Soluble model of Bose-atoms with two level internal structure: non-conventional Bose-Einstein condensation

Condensed Matter Physics, 2010
For a Bose atom system whose energy operator is diagonal in the so-called number operators and its ground state has an internal two-level structure with negative energies, exact expressions for the limit free canonical energy and pressure are obtained ...
M. Corgini, D.P. Sankovich
doaj   +1 more source

Dynamical decoherence in a cavity with a large number of two-level atoms

, 2004
We consider a large number of two-level atoms interacting with the mode of a cavity in the rotating-wave approximation (Tavis-Cummings model). We apply the Holstein-Primakoff transformation to study the model in the limit of the number of two-level atoms,
Aniello P, Bonifacio R, Bonifacio R, Frasca M, Gea-Banacloche J, Giulini D, Marco Frasca, Myatt C J, Namiki M, Persico F, Schleich W P, Zurek W H   +11 more
core   +1 more source