Results 81 to 90 of about 5,045,379 (328)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Open PhysicsThis study explores the dynamics of a two two-level atomic system interacting with a parity-deformed field, modeled as a coherent state. By varying the parity deformation parameter and incorporating the effects of intensity-dependent coupling, we examine
Abdel-Khalek Sayed +2 more
doaj +1 more source
PhotonicsWe propose a theoretical scheme to enhance quantum coherence and obtain steady-state coherence by combining quantum feedback control and noise-assisted preparation.
Chang-Xiao Li
doaj +1 more source
Fast and robust two- and three-qubit swapping gates on multi-atomic ensembles in quantum electrodynamic cavity [PDF]
Electronic Proceedings in Theoretical Computer Science, 2011 Creation of quantum computer is outstanding fundamental and practical problem. The quantum computer could be used for execution of very complicated tasks which are not solvable with the classical computers.
Sergey N. Andrianov, Sergey A. Moiseev
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Quantum correlations between each two-level system in a pair of atoms and general coherent fields
Results in Physics, 2016 The quantitative description of the quantum correlations between each two-level system in a two-atom system and the coherent fields initially defined in a coherent state in the framework of power-law potentials (PLPCSs) is considered.
S. Abdel-Khalek +2 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Light squeezing it two-atom Jaynes - Cummings model with intensity-dependent atom-field coupling
Физика волновых процессов и радиотехнические системы, 2014 The features of light squeezing for two two-level atom interacting with a coherent field in finite-Q cavity taking into account dependence of atom-field coupling from intensity of a field are explored.
E.K. Bashkirov
doaj