Results 31 to 40 of about 1,247,885 (263)

Two-phase flow in a narrow annular channel between stationary and rotating cylinders

open access: yesУчёные записки Казанского университета: Серия Физико-математические науки, 2021
The results of a numerical study of three-dimensional two-phase flow in a channel between coaxial cylinders, which arises due to axial pressure drop and rotation of the inner cylinder, are presented.
I.V. Morenko
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Heat Transfer Deterioration by the Copper Oxide Layer on Horizontal Subcooled Flow Boiling

open access: yesApplied Mechanics, 2023
Water–copper is one of the most common combinations of working fluid and heating surface in high-performance cooling systems. Copper is usually selected for its high thermal conductivity and water for its high heat transfer coefficient, especially in the
Edgar Santiago Galicia   +6 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

A MULTIPHASE FLOW LOOP DESIGN FOR INVESTIGATING THE PARTIAL PHASE SEPARATION IN A PIPE TEE

open access: yesActa Polytechnica, 2019
This article presents a design and commissioning of a multiphase flow loop, which was developed for scrutinizing the partial phase separation characteristics of pipe Tees. Its length is 9m and its primary diameter is 0.078m (3 inches).
Ahmed Saieed   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Development of the pressure drop model for two-phase flow through a packed bed with small particles

open access: yesNihon Kikai Gakkai ronbunshu, 2014
Pressure drop tests of single-phase and two-phase flows through a packed bed with micrometer size diameter particles under laminar upward flow conditions were carried out to develop the new pressure drop model for two-phase flow through a packed bed.
Hideaki HOSOI   +4 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Lattice Boltzmann Method simulation of wellbore gas–liquid​ phase transition

open access: yesEnergy Reports, 2022
Whenever the drilling wellbore is at the state of gas–liquid two-phase flow, gas slips and migrates along the drilling fluid. Due to the decreased wellbore temperature and pressure during gas migration, gas volume will gradually increase.
Shihui Sun   +4 more
doaj   +1 more source

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