Results 111 to 120 of about 17,766,923 (318)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

[Stage Two Landscapes 10]

, 2003
Wet on wet landscape of several buildings in blue, green, orange, red and white along water; brown sky.Tiff file: 2400x3426 pixels, 23.5 Mb; Display: jpeg, 552x800 pixels ...
Father Edward Catich
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

No dislocation rate gap between single and two-stage revisions with a cementless Dual Mobility Cup

SICOT-J
Introduction: A major complication of hip arthroplasty is dislocation. In revision, the rate of dislocation is even higher, especially among patients with hip prosthetic joint infection treated with two-stage surgery.
Bidard Justine, Elhadjene Nory, Zadel Nicolas, Neri Thomas, Farizon Frédéric, Boyer Bertrand   +5 more
doaj   +1 more source

[Stage Two Landscapes 21]

, 2003
Wet on wet landscape of several houses in grey, red, white and yellow with dark grey sky.Tiff file: 2290x2810 pixels, 18.4 Mb; Display: jpeg, 572x703 pixels ...
Father Edward Catich
core  

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Administrative dispute and the administrative adjudication process in contemporary serbia -some problems of reform and amendment directions-

Zbornik Radova Pravnog Fakulteta u Splitu, 2010
The subject of this paper is the functioning of one part of the new judicial system in Serbia put in place by judicial law in 2008, and based on the Serbian Constitution of 2006. It deals with the administrative judiciary, i.e. administrative dispute and
Zoran R. Tomić
doaj  

A Constraint-Tightening Feasible-Trajectory-Guided Two-Stage Evolutionary Algorithm

Mathematics
Constrained multi-objective optimization problems (CMOPs) are widely encountered in practical engineering and scientific applications. To address these issues, this paper proposes a Constraint-Tightening Feasible-Trajectory-Guided Two-Stage Evolutionary ...
Dapeng Wei, Kai Song, Yahui Shan, Guangyin Jin   +3 more
doaj   +1 more source

[Stage Two Landscapes 14]

, 2003
Wet on wet landscape of evergreen trees, grey and yellow foreground, purple sky.Tiff file: 2319x3351 pixels, 22.2 Mb; Display: jpeg, 557x800 pixels ...
Father Edward Catich
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source