Results 161 to 170 of about 683,782 (308)

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Channel estimation algorithm for OTFS based on basis expansion model with bidirectional LSTM network

Tongxin xuebao
Accurate channel estimation is critical for the reliable deployment of orthogonal time frequency space (OTFS) systems in 6G high-mobility scenarios.
Huang Ziyi, Li Guoquan, Lin Jinzhao, Pang Yu, Wu Ruiheng   +4 more
doaj  

Two-Stage Estimation of Overall Survival in the Phase 3 CheckMate 9ER Trial, Adjusting for the Impact of Subsequent Therapy. [PDF]

Oncol Ther
Grimm MO, Karim E, Kapetanakis V, Lothgren M, Ogareva A, Shukla P, Truscott J, Porta C.   +7 more
europepmc   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Augmented two-stage estimation for treatment switching in oncology trials: Leveraging external data for improved precision. [PDF]

Stat Methods Med Res
Campbell H, Latimer N, Jansen JP, Cope S.   +3 more
europepmc   +1 more source

Small Area Estimation with Skewed Data

, 2006
In business surveys, data typically are skewed and the standard approach for small area estimation based on linear mixed models lead to inefficient estimates.
Chandra, Hukum, Chambers, Ray
core  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Robustness test of the Heckman two-stage estimation method.

Robustness test of the Heckman two-stage estimation method.
Caihong Wen (17904307)
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Inference Regarding Multiple Structural Changes in Linear Models Estimated via Two Stage Least Squares.

, 2005
Bai and Perron(1998) develop methods that are designed to test for structural stability with an unknown number of break points in the sample. Their analysis is in the context of linear regression models estimated via Ordinary Least Squares(OLS).
Han, Sanggohn
core