Results 11 to 20 of about 20,294,309 (198)

Laparoscopic first step approach in the two stage hepatectomy. [PDF]

Hepatobiliary Surg Nutr, 2015
Resection is the gold standard therapeutic option for patients with colorectal liver metastases. However, only 20-30% of patients are resectable. In patients with a concomitant future liver remnant (FLR) less than 25-30%, a single stage resection is not ...
Levi Sandri GB, Colace L, Vennarecci G, Santoro R, Lepiane P, Colasanti M, Burocchi M, Ettorre GM.   +7 more
europepmc   +2 more sources

Two-stage laparoscopic resection of giant hepatoblastoma in infants combined with liver partial partition and artery ligation

World Journal of Surgical Oncology, 2021
Purpose Laparoscopic resection of giant hepatoblastoma (HB) in children has long been a subject of controversy. Here, a new procedure of two-stage laparoscopic resection of giant HB in infants was firstly reported and the feasibility was discussed ...
Yaohao Wu, Lexiang Zeng, Ronglin Qiu, Jie Zhang, Jianhang Su, Minyi Liao, Xiaogeng Deng   +6 more
doaj   +1 more source

One Step at a Time: A Pediatric Case of Primary Two Staged Liver Transplantation in a Child with ESLD

Transplantology, 2022
Toxic liver syndrome is a rare condition with multiorgan failure in end-stage liver disease (ESLD), and a two-stage LT following hepatectomy with a prolonged anhepatic phase is an accepted approach to bridge to transplant.
Eberhard Lurz, Elisabeth Klucker, Karl Reiter, Robert Dalla Pozza, Jens Werner, Markus Guba, Michael Berger   +6 more
doaj   +1 more source

Current status of associating liver partition with portal vein ligation for staged hepatectomy: Comparison with two-stage hepatectomy and strategies for better outcomes. [PDF]

World J Gastroenterol, 2019
Since its introduction in 2012, associating liver partition with portal vein ligation for staged hepatectomy (ALPPS) has significantly expanded the pool of candidates for liver resection.
Au KP, Chan ACY.
europepmc   +2 more sources

Associated Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS) Registry: What Have We Learned?

Gut and Liver, 2020
In 2007, the first associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) procedure was performed in Regensburg, Germany. ALPPS is a variation of twostage hepatectomy to induce rapid liver hypertrophy allowing the removal of ...
Hauke Lang, Janine Baumgart, Jens Mittler   +2 more
doaj   +1 more source

c‐Rel–dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis

Hepatology, EarlyView., 2022
In response to genotoxic injury, c‐Rel upregulates ATM‐Chk2‐p53 pathway DNA damage proteins to limiting hepatocarcinogenesis. Abstract Background and Aims Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death. The NF‐κB transcription factor family subunit c‐Rel is typically protumorigenic; however, it has recently been reported as a
Jack Leslie, Jill E. Hunter, Amy Collins, Amelia Rushton, Lauren G. Russell, Erik Ramon‐Gil, Maja Laszczewska, Misti McCain, Marco Y. W. Zaki, Amber Knox, Yixin Seow, Laura Sabater, Daniel Geh, Neil D. Perkins, Helen L. Reeves, Dina Tiniakos, Derek A. Mann, Fiona Oakley   +17 more
wiley   +1 more source

Two-stage liver transplantation in a surgically complicated liver failure patient after hepatic tumor resection -A case report- [PDF]

Korean Journal of Anesthesiology, 2010
Two-stage liver transplantation, involving a total hepatectomy with a temporary portocaval shunt followed by liver transplantation, requires intensive perioperative care, especially during the prolonged anhepatic period.
Sang Hyun Lee, Soo Hyun Yang, Gaab Soo Kim   +2 more
doaj   +1 more source

TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk

Hepatology, EarlyView., 2022
The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam, Jianqing Yu, Hao Huang, Xiaofan Ding, Alissa M. Wong, Howard H. Leung, Anthony W. Chan, Kelvin K. Ng, Mingjing Xu, Xin Wang, Nathalie Wong   +10 more
wiley   +1 more source

Clinical Application of Indocyanine Green Fluorescence Imaging in the Resection of Hepatoblastoma: A Single Institution's Experiences

Frontiers in Surgery, 2022
PurposeIndocyanine green (ICG) fluorescence imaging is becoming increasingly popular in adult oncologic surgery, but remains relatively uncommon in pediatric oncologic surgery.
Yuanchao Shen, Manna Zheng, Jiahao Li, Tianbao Tan, Jiliang Yang, Jing Pan, Chao Hu, Yan Zou, Tianyou Yang   +8 more
doaj   +1 more source

Precision surgery for colorectal liver metastases: Current knowledge and future perspectives

Annals of Gastroenterological Surgery, 2022
Precision surgery for colorectal liver metastases (CRLM) includes optimal selection of both the patient and surgery. Initial attempts of using clinical risk scores to identify patients for whom technically feasible surgery is oncologically futile failed.
Georgios Antonios Margonis, Jean‐Nicolas Vauthey   +1 more
doaj   +1 more source