Results 31 to 40 of about 23,757 (245)

Two-stage laparoscopic resection of giant hepatoblastoma in infants combined with liver partial partition and artery ligation

open access: yesWorld Journal of Surgical Oncology, 2021
Purpose Laparoscopic resection of giant hepatoblastoma (HB) in children has long been a subject of controversy. Here, a new procedure of two-stage laparoscopic resection of giant HB in infants was firstly reported and the feasibility was discussed ...
Yaohao Wu   +6 more
doaj   +1 more source

One Step at a Time: A Pediatric Case of Primary Two Staged Liver Transplantation in a Child with ESLD

open access: yesTransplantology, 2022
Toxic liver syndrome is a rare condition with multiorgan failure in end-stage liver disease (ESLD), and a two-stage LT following hepatectomy with a prolonged anhepatic phase is an accepted approach to bridge to transplant.
Eberhard Lurz   +6 more
doaj   +1 more source

Associated Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS) Registry: What Have We Learned?

open access: yesGut and Liver, 2020
In 2007, the first associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) procedure was performed in Regensburg, Germany. ALPPS is a variation of twostage hepatectomy to induce rapid liver hypertrophy allowing the removal of ...
Hauke Lang   +2 more
doaj   +1 more source

c‐Rel–dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis

open access: yesHepatology, EarlyView., 2022
In response to genotoxic injury, c‐Rel upregulates ATM‐Chk2‐p53 pathway DNA damage proteins to limiting hepatocarcinogenesis. Abstract Background and Aims Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death. The NF‐κB transcription factor family subunit c‐Rel is typically protumorigenic; however, it has recently been reported as a
Jack Leslie   +17 more
wiley   +1 more source

TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk

open access: yesHepatology, EarlyView., 2022
The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam   +10 more
wiley   +1 more source

Viability assessment and transplantation of fatty liver grafts using end‐ischemic normothermic machine perfusion

open access: yesLiver Transplantation, EarlyView., 2022
Abstract End‐ischemic viability testing by normothermic machine perfusion (NMP) represents an effective strategy to recover liver grafts having initially been discarded for liver transplantation (LT). However, its results in the setting of significant (≥30%) macrovesicular steatosis (MaS) have not been specifically assessed.
Damiano Patrono   +8 more
wiley   +1 more source

Locoregional treatment for colorectal liver metastases aiming for precision medicine

open access: yesAnnals of Gastroenterological Surgery, 2023
In patients with colorectal liver metastases (CLM), surgery is potentially curative. The use of novel surgical techniques and complementary percutaneous ablation allows for curative‐intent treatment even in marginally resectable cases.
Harufumi Maki   +5 more
doaj   +1 more source

Adjuvant Transarterial Chemoembolization for Barcelona Clinic Liver Cancer Stage A Hepatocellular Carcinoma After Hepatectomy

open access: yesFrontiers in Oncology, 2020
IntroductionThe care for patients with hepatocellular carcinoma (HCC) is challenging. This study is to evaluate the effect of adjuvant transarterial chemoembolization (TACE) for Barcelona Clinic Liver Cancer (BCLC) stage A HCC patients after hepatectomy ...
Yue-Lin Zhang   +27 more
doaj   +1 more source

The Evolution of Associating Liver Partition with Portal Vein Ligation for Staged Hepatectomy

open access: yesSiriraj Medical Journal, 2022
Associating Liver Partition with Portal Vein Ligation for Staged Hepatectomy is a cutting-edge surgical technique for resection of hepatic malignancies that has piqued the interest of the international hepatobiliary community.
Voramon Teranasthiarphan   +3 more
doaj   +1 more source

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