Results 31 to 40 of about 215,084 (309)

Evaluation of Two Stage Modified Ridge Estimator and Its Performance

Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2018
Biasedestimation methods are more desirable than two stage least squares estimationfor simultaneous equations models suffering from the problem ofmulticollinearity.
Selma Toker, Nimet Özbay
doaj   +1 more source

Estimation of Large-Scale Implicit Models Using 2-Stage Methods [PDF]

Modeling, Identification and Control, 1985
The problem of estimating large scale implicit (non-recursive) models by two- stage methods is considered. The first stage of the methods is used to construct or estimate an explicit form of the total model, by constructing a minimal stochastic ...
Rolf Henriksen
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Two-stage least squares as minimum distance [PDF]

The Econometrics Journal, 2019
SummaryThe two-stage least-squares (2SLS) instrumental-variables (IV) estimator for the parameters in linear models with a single endogenous variable is shown to be identical to an optimal minimum-distance (MD) estimator based on the individual instrument-specific IV estimators.
openaire   +3 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Convex Combination of Ordinary Least Squares and Two-stage Least Squares Estimators

, 2015
In the presence of confounders, the ordinary least squares (OLS) estimator is known to be biased. This problem can be remedied by using the two-stage least squares (TSLS) estimator, based on the availability of valid instrumental variables (IVs). This reduction in bias, however, is offset by an increase in variance.
Ginestet, Cedric E., Emsley, Richard, Landau, Sabine   +2 more
openaire   +2 more sources

Impact of macroeconomic conditions on presidential approval rating

Estudos Econômicos
This paper investigates the relationship between macroeconomic indicators and presidential approval ratings in Brazil spanning from 1996 to 2023.
Marcelo Kfoury Muinhos, Matheus Rodrigues   +1 more
doaj   +1 more source

EXTERNAL FACTORS WITH GOVERNMENT AND COMPANY POLICIES THAT HAVE AN IMPACT ON THE DEBT SERVICE COVERAGE RATIO OF COAL COMPANIES

Jurnal Aplikasi Manajemen, 2020
Coal companies are industries that require large capital in building their industries, therefore companies must be able to know what external factors and internal factors that can affect financial performance and DSCR.
Irwan Hermawan, Bonar M. Sinaga, Trias Andati   +2 more
doaj   +1 more source

The cost-saving effect of continuity of care (COC): an analysis of institutional COC on diabetic treatment costs using panel 2SLS regressions

BMC Health Services Research, 2021
Background The high costs of chronic conditions call for new treatment approaches that reduce costs while ensuring desirable health outcomes. There has been a growing transformation of care delivery models from conventional referral systems to integrated
Yu-Ping Wen, Sandra S. Liu, Ji-Tian Sheu, Hong-Huei Wang, Edmund R. Becker, Jui-fen Rachel Lu   +5 more
doaj   +1 more source