Results 101 to 110 of about 970,960 (297)
Optimal regression estimator for stratified two-stage sampling
Regression estimators are often used in survey sampling for point estimation. We propose a new regression estimator based upon the optimal estimator proposed by Berger et al., (2003).
Yves G. Berger +3 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Traditional survey methods may cause refusals to respond or untruthful replies when encounter the sensitive questions. The Randomized Response Technique (RRT) is designed to decrease social desirability bias and obtain reliable estimates.
Xiangyu Chen +5 more
doaj
A Novel Two-Stage Gas-Excitation Sampling and Sample Delivery Device: Simulation and Experiments
Asteroids are remnants of primordial material from the early stages of solar system formation, approximately 4.6 billion years ago, and they preserve invaluable records of the processes underlying planetary evolution.
Xu Yang +3 more
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
A simulative study on estimations in two-stage random sampling
碩士 抽樣調查以有限人力及經費,獲得所需資訊,為近年來應用甚廣的學科;惟一般抽樣調查偏重於抽樣方法之設計,忽略估計式的選擇,事實上選擇適當的估計式可減少抽樣誤差的產生,對講求效率與準確度的抽樣調查而言,其重要性不下於抽樣方法的設計。 本研究要旨首先探討(SRS,STS)二段隨機抽樣設計的理論,由於理論驗證困難,因此,本文以模擬分析,比較在某些母體特徵情況下估計值的大小,期望選擇適當估計式使調查結果之抽樣誤差減少,並提高可信度。 本研究內容摘要如下: 1.探討母體平均數的估計式。 2 ...
楊靜芬; Yang, Ching-fen
core
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source

