Results 131 to 140 of about 970,960 (297)
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Consistency of estimators and variance estimators for two-stage sampling
, 2018 Two-stage sampling designs are commonly used for household and health surveys. To produce reliable estimators with assorted confidence intervals, some basic statistical properties like consistency and asymptotic normality of the Horvitz-Thompson ...
Vallée, Audrey-Anne, Chauvet, Guillaume
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Analytical Science AdvancesCannabis inflorescences represent an important source of many high‐value bioactive specialized metabolites, among which the family of terpenes or terpenoids that are the largest classes of natural products known.
Marco De Poli +5 more
doaj +1 more source
MathematicsIn this paper, we suggest using a partial randomized response model using Poisson distribution to efficiently estimate a rare sensitive attribute by applying the probability proportional to size (PPS) sampling method when the population is composed of ...
Gi-Sung Lee +2 more
doaj +1 more source
Sampling for Subpopulations in Two-Stage Surveys
, 2008 Many national household interview surveys aim to produce statistics on small subpopulations, such as specific ethnic groups or the indigenous population of a country. In most countries, there is no reliable frame of the sub-populations of interest, so it
Robert Clark (20120022)
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Cambridge Prisms: Global Mental HealthAdolescence is a critical period marked by significant physical and psychological changes, yet there is limited understanding of suicidal behaviors among adolescents in Bangladesh.
Firoj Al-Mamun +5 more
doaj +1 more source
Initial sample size selection for the two-stage sampling procedure
, 2013 碩士在常態分布母體下，當變異數未知且不相等時，Bishop and Dudewicz(1978)提出二階段抽樣程序方法來檢定母體平均數是否相等。二階段抽樣程序是一種屬於實驗設計的方法，其先決定第一階段的初始樣本數，然後在第二階段收集更多的樣本。本文討倫其初始樣本數和最後總樣本數之間的關係。本文另提供兩個指標T和R來幫助選取初始樣本數。When observations are taken from populations that are normally distributed with ...
許育賓; Hsu, Yu-Pin
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