Results 51 to 60 of about 1,433,334 (259)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Composable security for practical quantum key distribution with two way classical communication

open access: yesNew Journal of Physics, 2021
We present a theory for the composable security of sending-or-not-sending (SNS) protocol of twin field quantum key distribution (TF-QKD). We present methods to strictly calculate the finite-key effects in QKD with error rejection through two-way ...
Cong Jiang   +3 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

A Retrodirective Array Enabled by CMOS Chips for Two-Way Wireless Communication with Automatic Beam Tracking

open access: yesEngineering
This article proposes and demonstrates a retrodirective array (RDA) for two-way wireless communication with automatic beam tracking. The proposed RDA is enabled by specifically designed chips made using a domestic complementary metal-oxide semiconductor (
Jiacheng Guo   +4 more
doaj   +1 more source

Employee voice: speaking up in organisation as a correlate of employee productivity in oil and gas industry - an empirical investigation from Nigeria [PDF]

open access: yesSerbian Journal of Management, 2019
The understanding and interpretation of voice have been given critical attention among researchers, practitioners in recent years. The firm believes of the workforce that they can openly express their personal opinion and concerns to higher authority in ...
Olusegun Emmanuel Akinwale
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Multiserver Retrial Queue with Two-Way Communication and Synchronous Working Vacation

open access: yesMathematics
This work investigates a two-way communication retrial queue with synchronous working vacation and a constant retrial policy. During the idle time, a server makes an outgoing call after a random length.
Tzu-Hsin Liu   +3 more
doaj   +1 more source

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