Results 151 to 160 of about 3,741,194 (297)

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

The Recognition Algorithm of Two-Phase Flow Patterns Based on GoogLeNet+5 Coord Attention. [PDF]

Micromachines (Basel), 2023
Zhang J, Wei X, Wang Z.
europepmc   +1 more source

Gas-Water Two-Phase Flow Mechanisms in Deep Tight Gas Reservoirs: Insights from Nanofluidics. [PDF]

Nanomaterials (Basel)
Pei X, Dai L, Wang C, Zhong J, Ren X, Wang Z, Peng C, Zhang Q, Zhang N.   +8 more
europepmc   +1 more source

Optimization for Pipeline Corrosion Sensor Placement in Oil-Water Two-Phase Flow Using CFD Simulations and Genetic Algorithm. [PDF]

Sensors (Basel), 2023
Shi S, Jiang B, Ludwig S, Xu L, Wang H, Huang Y, Yan F.   +6 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Numerical simulation study of gas-solid two-phase flow characteristics in borehole sampling of coal cuttings. [PDF]

PLoS One
Xue S, Zhang L, Zheng X, Gao C, Liu S.
europepmc   +1 more source

Surface Modification of 3D Printed Microfluidic Devices for Controlled Wetting in Two-Phase Flow. [PDF]

Micromachines (Basel), 2022
Warr CA, Crawford NG, Nordin GP, Pitt WG.   +3 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Gas-liquid two-phase flow-based triboelectric nanogenerator with ultrahigh output power. [PDF]

Sci Adv, 2022
Dong Y, Xu S, Zhang C, Zhang L, Wang D, Xie Y, Luo N, Feng Y, Wang N, Feng M, Zhang X, Zhou F, Wang ZL.   +12 more
europepmc   +1 more source