Results 21 to 30 of about 454,650 (72)

Recent advances in therapeutic strategies for triple-negative breast cancer

open access: yesJournal of Hematology & Oncology, 2022
Triple-negative breast cancer (TNBC) is the most malignant subtype of breast cancer (BC) with a poor prognosis. Current treatment options are limited to surgery, adjuvant chemotherapy and radiotherapy; however, a proportion of patients have missed the ...
Yun R Li   +6 more
semanticscholar   +1 more source

Sacituzumab Govitecan in Metastatic Triple-Negative Breast Cancer

open access: yesNew England Journal of Medicine, 2021
Copyright © 2021 Massachusetts Medical Society. BACKGROUND Patients with metastatic triple-negative breast cancer have a poor prognosis. Sacituzumab govitecan is an antibody–drug conjugate composed of an antibody targeting the human trophoblast cell ...
A. Bardia   +29 more
semanticscholar   +1 more source

Triple negative breast cancer: Pitfalls and progress

open access: yesnpj Breast Cancer, 2022
Triple negative breast cancer (TNBC) is characterized by the lack of estrogen and progesterone receptor expression and lacks HER2 overexpression or gene amplification.
P. Zagami, L. Carey
semanticscholar   +1 more source

Ferroptosis heterogeneity in triple-negative breast cancer reveals an innovative immunotherapy combination strategy.

open access: yesCell Metabolism, 2022
Treatment of triple-negative breast cancer (TNBC) remains challenging. Deciphering the orchestration of metabolic pathways in regulating ferroptosis will provide new insights into TNBC therapeutic strategies.
Fan Yang   +10 more
semanticscholar   +1 more source

Pathogenesis of Triple-Negative Breast Cancer

open access: yesAnnual Review of Pathology, 2022
Triple-negative breast cancer (TNBC) encompasses a heterogeneous group of fundamentally different diseases with different histologic, genomic, and immunologic profiles, which are aggregated under this term because of their lack of estrogen receptor ...
F. Derakhshan, J. Reis-Filho
semanticscholar   +1 more source

Measurement of the $ZZ$ production cross section in $pp$ collisions at $\sqrt{s}$ = 8 TeV using the $ZZ\to\ell^{-}\ell^{+}\ell^{\prime -}\ell^{\prime +}$ and $ZZ\to\ell^{-}\ell^{+}\nu\bar{\nu}$ channels with the ATLAS detector [PDF]

open access: yes, 2016
See paper for full list of authors - 55 pages in total, author list starting page 39, 9 figures, 11 tables, submitted to JHEP. All figures including auxiliary figures are available at https://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/STDM-2014-16 ...
Arce ATH   +999 more
core   +1 more source

The SU(3)-invariant sector of new maximal supergravity [PDF]

open access: yes, 2011
We investigate the SU(3)-invariant sector of the one-parameter family of SO(8) gauged maximal supergravities that has been recently discovered. To this end, we construct the N = 2 truncation of this theory and analyse its full vacuum structure.
M. Gul   +999 more
core   +1 more source

The microbial metabolite trimethylamine N-oxide promotes antitumor immunity in triple-negative breast cancer.

open access: yesCell Metabolism, 2022
Immunotherapy has achieved limited success in patients with triple-negative breast cancer (TNBC), an aggressive disease with a poor prognosis. Commensal microbiota have been proven to colonize the mammary gland, but whether and how they modulate the ...
Hai Wang   +19 more
semanticscholar   +1 more source

Triple-negative breast cancer molecular subtyping and treatment progress

open access: yesBreast Cancer Research, 2020
Triple-negative breast cancer (TNBC), a specific subtype of breast cancer that does not express estrogen receptor (ER), progesterone receptor (PR), or human epidermal growth factor receptor 2 (HER-2), has clinical features that include high invasiveness,
Li Yin   +3 more
semanticscholar   +1 more source

Triple-Negative Breast Cancer: A Brief Review About Epidemiology, Risk Factors, Signaling Pathways, Treatment and Role of Artificial Intelligence

open access: yesFrontiers in Molecular Biosciences, 2022
Triple-negative breast cancer (TNBC) is a kind of breast cancer that lacks estrogen, progesterone, and human epidermal growth factor receptor 2. This cancer is responsible for more than 15–20% of all breast cancers and is of particular research interest ...
N. Almansour
semanticscholar   +1 more source

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