Results 151 to 160 of about 6,484,256 (294)

Bird Types in the Carnegie Museum List of Types of Birds in the Collection of the Carnegie Museum, on May 1, 1928 W. E. Clyde Todd [PDF]

, 1929
W. S.
openalex   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Development and recalibration of a multivariable type 1 diabetes prediction model for type 1 diabetes across multiple screening studies. [PDF]

BMC Med
Templeman EL, Ferrat LA, Parikh HM, You L, Triolo TM, Steck AK, Hagopian WA, Vehik K, Onengut-Gumuscu S, Gottlieb PA, Rich SS, Krischer JP, Redondo MJ, Oram RA, Type 1 diabetes TrialNet Study Group.   +14 more
europepmc   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

The pathophysiology, presentation and classification of Type 1 diabetes. [PDF]

Diabetes Obes Metab
Aamodt KI, Powers AC.
europepmc   +1 more source

Dr. Joel Asaph Allen—An Appreciation<xref ref-type="fn" rid="fn1">¹</xref>

, 1922
Edward William Nelson
openalex   +2 more sources

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Type 1 diabetes in Brazil: a narrative overview of the Brazilian Type 1 Diabetes Study Group. [PDF]

Diabetol Metab Syndr
Gomes MB, Negrato CA, Brazilian Diabetes Study Group.   +2 more
europepmc   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Unraveling the development of cutaneous neurofibromas in neurofibromatosis type 1. [PDF]

Acta Neuropathol Commun
Pulh P, Coulpier F, Onfroy A, Oubrou L, Zhang W, Toledano L, Abou Zougheib E, Fertitta L, Wolkenstein P, Topilko P.   +9 more
europepmc   +1 more source