Results 171 to 180 of about 19,606,378 (347)

Reinfection results in accumulation of unintegrated viral DNA in cytopathic and persistent human immunodeficiency virus type 1 infection of CEM cells. [PDF]

, 1990
C. David Pauza, J Galindo, D. D. Richman
openalex   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

A furin-defective cell line is able to process correctly the gp160 of human immunodeficiency virus type 1 [PDF]

, 1994
Yasuo Ohnishi, Tatsuo Shioda, Kazuhisa Nakayama, Shinya Iwata, Bin Gotoh, Michinari Hamaguchi, Yasuhiro Nagai   +6 more
openalex   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Subclinical Type 1 Diabetes [PDF]

Journal of the Royal Society of Medicine, 2002
Tahseen A, Chowdhury, Shawarna S, Lasker
openaire   +2 more sources

Bovine Viral Diarrhea Virus Cytopathic and Noncytopathic Biotypes and Type 1 and 2 Genotypes in Diagnostic Laboratory Accessions: Clinical and Necropsy Samples from Cattle [PDF]

, 2000
Robert W. Fulton, Jeremiah T. Saliki, Anthony W. Confer, Lurinda J. Burge, Jean M. d’Offay, R. Gayman Helman, Steven R. Bolin, Julia F. Ridpath, Mark E. Payton   +8 more
openalex   +1 more source

Risks and Prevalence of Diabetic Retinopathy in Children and Young People with Type 1 Diabetes Mellitus [PDF]

, 2020
Rebecca Thomas, Sze May Ng
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Changes in pancreatic exocrine function in young at‐risk children followed to islet autoimmunity and type 1 diabetes in the ENDIA study

, 2020
Megan A. S. Penno, Helena Oakey, P Augustine, Mario Taranto, Simon C. Barry, Peter G. Colman, Maria E. Craig, Elizabeth A. Davis, Lynne Giles, Mark Harris, Aveni Haynes, Kelly McGorm, Grant Morahan, Claire Morbey, William D. Rawlinson, Richard Sinnott, Georgia Soldatos, Rebecca L. Thomson, Peter Vuillermin, John M. Wentworth, Leonard C. Harrison, Jennifer Couper   +21 more
openalex   +2 more sources

Regulation of Type 1 Inositol 1,4,5-Trisphosphate–gated Calcium Channels by InsP3 and Calcium [PDF]

, 1999
Ion I. Moraru, Edward Kaftan, Barbara E. Ehrlich, J Watras   +3 more
openalex   +1 more source