Results 211 to 220 of about 19,606,378 (347)

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Type 1 Diabetes and Other Autoimmune Diseases-Epidemiology, Pathophysiology and Screening. [PDF]

Endocrinol Diabetes Metab
Kahaly GJ, Forst T, Kellerer M, Lanzinger S, Rötzer RD, Schott M, Schumm-Draeger PM.   +6 more
europepmc   +1 more source

MA-[D-Leu-4]-OB3, a small molecule synthetic peptide leptin mimetic, improves episodic memory, and reduces serum levels of tumor necrosis factor-alpha and neurodegeneration in mouse models of Type 1 and Type 2 Diabetes Mellitus

, 2020
Zall Hirschstein, Gautam R Vanga, Guirong Wang, Zachary M. Novakovic, Patricia Grasso   +4 more
openalex   +2 more sources

Characterization of the functional properties of env genes from long-term survivors of human immunodeficiency virus type 1 infection [PDF]

, 1996
Ruth I. Connor, Kristine E. Sheridan, C.Y. Lai, L Zhang, David D. Ho   +4 more
openalex   +1 more source

Type 1 Diabetes Mellitus in Children: Diagnosis and Management

, 2023
Rike Delya Rizkina, Ananda Rizkia, Donna Diva Widyantari, Ghina Syafinatunnajah, Grandis Cristagalli, Grandis Cristagalli, Irsyadina Hasana Bharata, Izza Mufida, Yoga Pamungkas Susani   +8 more
openalex   +2 more sources

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Genetic Risk and Transition Through Preclinical Stages of Type 1 Diabetes. [PDF]

J Clin Endocrinol Metab
Steck AK, Parikh HM, Triolo TM, Ferrat L, You L, Gottlieb PA, Oram RA, Onengut-Gumuscu S, Krischer JP, Rich SS, Redondo MJ.   +10 more
europepmc   +1 more source

Pseudouridine and 1-Ribosylpyridin-4-One-3-Carboxamide (PCNR) Serum Concentrations in Human Immunodeficiency Virus Type 1-Infected Patients Are Independent Predictors for AIDS Progression [PDF]

, 1996
Mariano Intrieri, Giuseppe Calcagno, G Oriani, Fabrizio Pane, Federica Zarrilli, Pietro Cataldo, Maria Foggia, M Piazza, Francesco Salvatore, Lucia Sacchetti   +9 more
openalex   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Are We Ready With Prevention for Type 1 Diabetes? [PDF]

Diabetes Metab Res Rev
Maines E, Franceschi R, Candia FD, Mozzillo E.   +3 more
europepmc   +1 more source