Results 291 to 300 of about 19,606,378 (347)

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Regulatory T cell dysfunction and immunotherapeutic breakthroughs in type 1 diabetes. [PDF]

open access: yesFront Endocrinol (Lausanne)
Zhou KJ   +6 more
europepmc   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Bridging pleiotropic mechanisms in leprosy type-1 reactions and neurodegenerative diseases. [PDF]

open access: yesSci Rep
Fava VM   +9 more
europepmc   +1 more source

Tips and Pitfalls of Surgical Techniques for Scoliotic Deformities in Neurofibromatosis Type 1. [PDF]

open access: yesJ Clin Med
Kaspiris A   +8 more
europepmc   +1 more source

Humanized Mouse Models for Type 1 Diabetes. [PDF]

open access: yesCurr Protoc
Serreze DV, Tousey-Pfarrer M, Racine JJ.
europepmc   +1 more source

Delving into the genome of resurged Shigella dysenteriae Type 1. [PDF]

open access: yesOne Health Outlook
Pragasam AK   +8 more
europepmc   +1 more source

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