Results 131 to 140 of about 2,420,770 (348)

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

The Impact of Tilburg Frailty on Poststroke Fatigue in First‐Ever Stroke Patients: A Cross‐Sectional Study With Unified Measurement Tools and Improved Statistics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Poststroke fatigue (PSF) and frailty share substantial overlap in their manifestations, yet previous research has yielded conflicting results due to the use of heterogeneous frailty assessment tools. Objective To evaluate the independent impact of frailty on PSF using a unified measurement system (Tilburg Frailty Indicator, TFI ...
Chuan‐Bang Chen, Xiao‐Xue Wang, Shao‐Rui Bao, Sui‐Li Lin, Mei‐Chun Shu, Xi‐Xi Ye, Wen‐Jie Cong   +6 more
wiley   +1 more source

AiDAPT: automated insulin delivery amongst pregnant women with type 1 diabetes: a multicentre randomized controlled trial – study protocol [PDF]

, 2022
Tara Lee, Corinne Collett, Mei‐See Man, Matthew Hammond, Lee Shepstone, Sara Hartnell, Eleanor Gurnell, Caroline Byrne, Eleanor Scott, Robert S. Lindsay, Damian Morris, Anna Brackenridge, Anna R. Dover, Rebecca M. Reynolds, Katharine F. Hunt, David R. McCance, Katharine Barnard‐Kelly, David Rankin, Julia Lawton, Laura E. Bocchino, Judy Sibayan, Craig Kollman, Malgorzata E. Wilinska, Roman Hovorka, Helen Murphy, Katharine F. Hunt, Helen Rogers, Damian Morris, Duncan Fowler, Josephine Rosier, Zeenat Banu, Sarah Barker, Gerry Rayman, Eleanor Gurnell, Caroline Byrne, Andrea Lake, Katy Davenport, Jeannie Grisoni, Shannon Savine, Helen Murphy, Tara Lee, T. M. Wallace, Alastair McKelvey, Elizabeth Turner, Nina Willer, Corinne Collett, Mei‐See Man, Emma Flanagan, Matthew Hammond, Lee Shepstone, Anna Brackenridge, Sara L. White, Anna Reid, Olanike Okolo, Eleanor Scott, Del Endersby, Anna R. Dover, Frances Dougherty, Susan Johnston, Rebecca M. Reynolds, Robert S. Lindsay, David Carty, Sharon Mackin, Isobel Crawford, Ross Buchan, David R. McCance, Louisa Jones, Joanne Quinn, Sarah Cains, Göher Ayman, Goher Ayman   +70 more
openalex   +1 more source

Subclinical Type 1 Diabetes [PDF]

Journal of the Royal Society of Medicine, 2002
Tahseen A, Chowdhury, Shawarna S, Lasker
openaire   +2 more sources

Prediction Model for Etiologic Differentiation of Isolated Vestibular Syndrome in Emergency Settings

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to develop and validate a predictive model for differentiating central from peripheral etiologies in patients with isolated vestibular syndrome (VS). Methods In this multicenter retrospective cohort study, 506 patients with isolated VS from five hospitals were divided into derivation (n = 301) and validation (n = 205)
Guo Wenting, Du Liping, Yang Yi, Hu Jin, Ye Bijun, Wang Jianer, Liu Shuangsi, Guo Shunyuan, Cai Xiaofeng, Wang Huiyuan, Wu Bin, Yu Xiang, Shi Tianming   +12 more
wiley   +1 more source

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin, Haocheng Yang, Feng Liu, Sihao Lin, Junru Hu, Jian Wang, Yulan Gou   +6 more
wiley   +1 more source

Targeted proteomics analysis in type 1 diabetes identifies lower agouti-related protein levels in individuals with impaired hypoglycaemia awareness

Scientific Reports
Impaired awareness of hypoglycaemia (IAH) is a complication of diabetes treatment, whereby individuals are no longer able to feel an oncoming hypoglycaemic event.
Rita D. M. Varkevisser, Agnese Petrera, Stefanie M. Hauck, Dick Mul, Henk-Jan Aanstoot, Andrew Paterson, Bruce H. R. Wolffenbuttel, Melanie M. van der Klauw, Dutch Type 1 Diabetes Biomarker Group   +8 more
doaj   +1 more source

Urocortin 2 Gene Transfer Improves Glycemic Control and Reduces Retinopathy and Mortality in Murine Insulin Deficiency. [PDF]

, 2020
Type 1 diabetes affects 20 million patients worldwide. Insulin is the primary and commonly the sole therapy for type 1 diabetes. However, only a minority of patients attain the targeted glucose control and reduced adverse events.
Bhargava, Raag, Gao, Mei Hua, Giamouridis, Dimosthenis, Guo, Tracy, Hammond, H Kirk, Huu, Viet Anh Nguyen, Kim, Young Chul, Lai, N Chin, Lantier, Louise, Skowronska-Krawczyk, Dorota, Xia, Bing   +10 more
core  

Obesity in Patients with Type 1 Diabetes: Links, Risks and Management Challenges

, 2021
Núria Vilarrasa, Patricia San José, Miguel A. Rubio, Albert Lecube   +3 more
openalex   +2 more sources

Apolipoprotein CIII Is an Important Piece in the Type-1 Diabetes Jigsaw Puzzle [PDF]

, 2021
Ismael Valladolid‐Acebes, Per‐Olof Berggren, Lisa Juntti‐Berggren   +2 more
openalex   +1 more source