Unleashing the Power of Multiomics: Unraveling the Molecular Landscape of Peripheral Neuropathy
ABSTRACT Peripheral neuropathies (PNs) affect over 20 million individuals in the United States, manifesting as a wide range of sensory, motor, and autonomic nerve symptoms. While various conditions such as diabetes, metabolic disorders, trauma, autoimmune disease, and chemotherapy‐induced neurotoxicity have been linked to PN, approximately one‐third of
Julie Choi+7 more
wiley +1 more source
An LMI-based Robust Fuzzy Controller for Blood Glucose Regulation in Type 1 Diabetes [PDF]
This paper presents a control algorithm for creating an artificial pancreas for type 1 diabetes, factoring in input saturation for a practical application. By utilizing the parallel distributed compensation and Takagi-Sugeno Fuzzy model, we design an optimal robust fuzzy controller. Stability conditions derived from the Lyapunov method are expressed as
arxiv
Reinforcement Learning-Based Adaptive Insulin Advisor for Individuals with Type 1 Diabetes Patients under Multiple Daily Injections Therapy [PDF]
The existing adaptive basal-bolus advisor (ABBA) was further developed to benefit patients under insulin therapy with multiple daily injections (MDI). Three different in silico experiments were conducted with the DMMS.R simulator to validate the approach of combined use of self-monitoring of blood glucose (SMBG) and insulin injection devices, e.g ...
arxiv
The lived experience of parents caring for a child with Type 1 diabetes : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Clinical Psychology at Massey University, Palmerston North, New Zealand [PDF]
Type 1 diabetes is the most common chronic metabolic condition seen in children and adolescents. Parents of children with Type 1 diabetes are responsible for carrying out a demanding treatment regimen on a daily basis, to prevent short- and long-term ...
Rifshana, Fathimath
core
Congenital rubella syndrome as a model for Type 1 (insulin-dependent) diabetes mellitus: increased prevalence of islet cell surface antibodies [PDF]
Fredda Ginsberg‐Fellner+11 more
openalex +1 more source
Development of a Disease Model for Predicting Postoperative Delirium Using Combined Blood Biomarkers
ABSTRACT Objective Postoperative delirium, a common neurocognitive complication after surgery and anesthesia, requires early detection for potential intervention. Herein, we constructed a multidimensional postoperative delirium risk‐prediction model incorporating multiple demographic parameters and blood biomarkers to enhance prediction accuracy ...
Hengjun Wan+7 more
wiley +1 more source
Shifting the paradigm of type 1 diabetes: a narrative review of disease-modifying therapies
A new diagnosis of type 1 diabetes (T1D) may be accompanied by numerous lifelong financial, emotional, and physical challenges, thus advancements in therapies that can delay the onset of clinical disease are crucial.
Alexander J. O’Donovan+3 more
doaj +1 more source
Islet cell and insulin autoantibodies in subjects at high risk for development of Type 1 (insulin-dependent) diabetes mellitus: the Lyon family study [PDF]
C. Thivolet+7 more
openalex +1 more source
Objective The National Institute of Health and Care Excellence (NICE) criteria for osteoarthritis (OA) obviate the need for physical examination or imaging, and their use may improve timely diagnosis of OA. However, they have not been validated. Methods Within a larger study of individuals with type 2 diabetes, participants with and without self ...
Lauren K. King+6 more
wiley +1 more source
“Conventional” and high carbohydrate/high fibre/low fat diets in adults with established Type 1 (insulin-dependent) diabetes [PDF]
T. D. R. Hockaday
openalex +1 more source