Results 191 to 200 of about 1,499,825 (316)

Adolescents' Experiences of Being a Sibling of a Child With Type 1 Diabetes: A Qualitative Study. [PDF]

Sci Diabetes Self Manag Care
Ludvigsen IE, Haugstvedt A.
europepmc   +1 more source

Therapy of Type 1 Diabetes [PDF]

Experimental and Clinical Endocrinology & Diabetes, 2019
Thomas, Haak, Stefan, Gölz, Andreas, Fritsche, Martin, Füchtenbusch, Thorsten, Siegmund, Elisabeth, Schnellbächer, Harald H, Klein, Til, Uebel, Diana, Droßel   +8 more
openaire   +3 more sources

3D‐Printed Corneal Substitutes: Materials, Fabrication, and Preclinical Progress

Advanced Materials Technologies, EarlyView.
Successful clinical translation of 3D‐printed corneal substitutes relies on the interplay between the bioink properties, cellular component, and the fabrication process. These factors influence the critical properties of the construct, including optical transparency, mechanical stability, suture retention, that ultimately govern long‐term stromal ...
Shadi Moshayedi, Ashley Vazquez, Alexander J. Choi, Dimitrios Karamichos, Jayoung Kim   +4 more
wiley   +1 more source

Evaluating Type 1 Diabetes Resources to Improve Awareness and Knowledge of Type 1 Diabetes Within Community Sport Settings. [PDF]

Endocrinol Diabetes Metab
Lim RJ, Parkinson AL, Roby HC, Roberts AG, Shetty VB, Taplin CE, Davis EA, Teo SYM.   +7 more
europepmc   +1 more source

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

Advanced Science, EarlyView.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu, Yumeng Zhang, Ye Wang, Xiaoyu Zhu, Ailin Yuan, Weijing Yin, Huangmin Yu, Xuemin Pang, Yufeng He, Yuchen Wang, Tong Wang, Yong Li, Yunlong Si   +12 more
wiley   +1 more source

Insulin regimens for adults living with type 1 diabetes mellitus. [PDF]

Cochrane Database Syst Rev
Taneri PE, Guo Y, Bongaerts B, Manne-Goehler J, Roglic G, Escobar Liquitay CM, Siegfried NL, Franco JV.   +7 more
europepmc   +1 more source

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

Advanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu, Ajun Geng, Ziyuan Li, Fanghao Guo, Jingqiang Wang, Xinyi Chen, Meiling Zhang, Yi Arial Zeng, Wen Li   +8 more
wiley   +1 more source

The Risk of Disease Progression of Type 1 Diabetes in First-Degree Relatives of People With Type 1 Diabetes: Design and Rationale of a Prospective, Longitudinal Study in China. [PDF]

Diabetes Obes Metab
Guo L, Luo X, Bi Y, Cao B, Dong G, Jiang S, Qin G, Qiao H, Shan Z, Yang T, Zhu G, Li M, Tang S, Zhang M, Li W.   +14 more
europepmc   +1 more source

Targeting UXS1‐Dependent Glucuronate Detoxification Potentiates Metformin's Anti‐Tumor Efficacy in Lung Adenocarcinoma

Advanced Science, EarlyView.
This study reveals that metformin promotes glucuronic acid metabolism in lung adenocarcinoma by activating UGDH S476 phosphorylation and enhancing the conversion of UDPG to UDPGA based on metabolomics analysis. Through compound virtual screening, it is found that plantainoside targeting UGDH downstream UXS1 leads to UDPGA toxicity accumulation ...
Qihai Sui, Zhencong Chen, Guangyao Shan, Zhengyang Hu, Xing Jin, Jiaqi Liang, Yanjun Yi, Jiacheng Yin, Haochun Shi, Xifei Jiang, Junjie Xi, Zongwu Lin, Cheng Zhan, Fenghao Sun, Wei Jiang   +14 more
wiley   +1 more source

Hypoglycemia Reporting in GLP-1RA Trials for Type 1 Diabetes: A Critical Gap That Needs To Be Addressed. [PDF]

Endocrinol Diabetes Metab
Ishtiaq S, Malik ZM, Ahmad AR.
europepmc   +1 more source