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Evolving type 1 diabetes in distinguishing between type 1 and type 2 diabetes
BMJ, 2020Distinguishing between newly diagnosed type 1 or type 2 diabetes can be challenging.1 As a nation, we are becoming more obese, thus increasing predisposition to type 2 diabetes, and we are more often recognising type 1 diabetes in older adults.23 This can blur the lines between type 1 and type 2 diabetes. All relevant factors should be considered when
N E, Hill, N S, Oliver
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Journal of Diabetes and its Complications, 2001
The purpose of this article is to review the available pathophysiological and clinical studies of patients with idiopathic Type 1 diabetes. Idiopathic Type 1 diabetes is a common form of diabetes most commonly seen in obese African American individuals living in large urban areas.
A, Piñero-Piloña, P, Raskin
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The purpose of this article is to review the available pathophysiological and clinical studies of patients with idiopathic Type 1 diabetes. Idiopathic Type 1 diabetes is a common form of diabetes most commonly seen in obese African American individuals living in large urban areas.
A, Piñero-Piloña, P, Raskin
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FP essentials, 2021
Type 1 diabetes is defined as a state of hyperglycemia due to insulin deficiency caused by autoimmune pancreatic beta-cell destruction. The risk among individuals in the general population has been estimated at 0.5%. A family history of diabetes and a personal history of conditions associated with type 1 diabetes (ie, autoimmune diseases) increase the ...
Magdalena, Pasarica +2 more
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Type 1 diabetes is defined as a state of hyperglycemia due to insulin deficiency caused by autoimmune pancreatic beta-cell destruction. The risk among individuals in the general population has been estimated at 0.5%. A family history of diabetes and a personal history of conditions associated with type 1 diabetes (ie, autoimmune diseases) increase the ...
Magdalena, Pasarica +2 more
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2003
Diabetes is a complex metabolic disorder diagnosed on the basis of hyperglycemia. Diagnostic criteria for the disorder are periodically revised (1). Diabetes may be classified mainly into types 1 and 2 based on the etiology and severity of insulin deficiency (1).
Yogish C. Kudva +2 more
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Diabetes is a complex metabolic disorder diagnosed on the basis of hyperglycemia. Diagnostic criteria for the disorder are periodically revised (1). Diabetes may be classified mainly into types 1 and 2 based on the etiology and severity of insulin deficiency (1).
Yogish C. Kudva +2 more
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2009
Type 1 diabetes is a life long metabolic disorder that is characterized by absolute insulin deficiency resulting in hyperglycemia and lipolysis. Type 1 diabetes accounts for 5–10% of the total diabetes population, the majority of the other patients has type 2 diabetes. Insulin deficiency originates with autoimmune mediated β-cell destruction.
Edith W.M.T. ter Braak +1 more
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Type 1 diabetes is a life long metabolic disorder that is characterized by absolute insulin deficiency resulting in hyperglycemia and lipolysis. Type 1 diabetes accounts for 5–10% of the total diabetes population, the majority of the other patients has type 2 diabetes. Insulin deficiency originates with autoimmune mediated β-cell destruction.
Edith W.M.T. ter Braak +1 more
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Nature Immunology, 2001
Type 1 diabetes is preventable in animal models and predictable in humans. The increase in our knowledge of basic immunology has allowed the initiation of large-scale clinical efforts to prevent diabetes.
Kai W. Wucherpfennig +1 more
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Type 1 diabetes is preventable in animal models and predictable in humans. The increase in our knowledge of basic immunology has allowed the initiation of large-scale clinical efforts to prevent diabetes.
Kai W. Wucherpfennig +1 more
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2017
This chapter discusses the epidemiology, genetics, and pathophysiology of type 1 diabetes including insulinitis and β-cell destruction in the Eisenbarth model of pathogenesis. Complications of type 1 diabetes and pregnancy are reviewed, and diagnosis and management are discussed.
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This chapter discusses the epidemiology, genetics, and pathophysiology of type 1 diabetes including insulinitis and β-cell destruction in the Eisenbarth model of pathogenesis. Complications of type 1 diabetes and pregnancy are reviewed, and diagnosis and management are discussed.
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2016
Type 1 (insulin-dependent) diabetes occurs worldwide and can appear at any age. The genetic susceptibility is strongly associated with HLA-DQ and DR on chromosome 6, but genetic factors on other chromosomes such as the insulin gene on chromosome 11 and the cytotoxic T-lymphocyte antigen gene on chromosome 2 may modulate disease risk.
Åke Lernmark, Shehab Alshiekh
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Type 1 (insulin-dependent) diabetes occurs worldwide and can appear at any age. The genetic susceptibility is strongly associated with HLA-DQ and DR on chromosome 6, but genetic factors on other chromosomes such as the insulin gene on chromosome 11 and the cytotoxic T-lymphocyte antigen gene on chromosome 2 may modulate disease risk.
Åke Lernmark, Shehab Alshiekh
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