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Diabetic nephropathy in type 1 diabetes
Minerva Medica, 2018Diabetic nephropathy (DN) also named diabetic kidney disease (DN) is one of the leading causes of mortality in people with diabetes. The aim of this review is to update the medical literature, the theories behind its early natural history, the pathways of its pathogenesis, its diagnosis and treatment.
Nikolaos Marketos +5 more
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Pediatric Diabetes, 2016
Environmental factors play an important role in the pathogenesis of type 1 diabetes and can determine if a genetically susceptible individual develops the disease. Increasing evidence suggest that among other exogenous agents certain virus infections can contribute to the beta-cell damaging process.
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Environmental factors play an important role in the pathogenesis of type 1 diabetes and can determine if a genetically susceptible individual develops the disease. Increasing evidence suggest that among other exogenous agents certain virus infections can contribute to the beta-cell damaging process.
openaire +3 more sources
, 2012 Type 1 diabetes is increasing in prevalence in different parts of the world. Type 1 diabetes is unique among autoimmune diseases in not having a clear female predisposition. Gender differences are present for the pattern of complications in patients with type 1 diabetes, especially with regard to cardiovascular complications.
Simon Coppack +3 more
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2011
Type 1 Diabetes (2011) has been completely updated for the 2nd edition. The background is introduced with a review of aetiology, classification, and presentation in young people and adults. The major longitudinal studies (DCCT/EDIC, Pittsburgh, and FinnDiane) are discussed and their importance in defining the long-term outcomes of Type 1 diabetes in ...
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Type 1 Diabetes (2011) has been completely updated for the 2nd edition. The background is introduced with a review of aetiology, classification, and presentation in young people and adults. The major longitudinal studies (DCCT/EDIC, Pittsburgh, and FinnDiane) are discussed and their importance in defining the long-term outcomes of Type 1 diabetes in ...
openaire +2 more sources
, 2009 Type 1 diabetes is a life long metabolic disorder that is characterized by absolute insulin deficiency resulting in hyperglycemia and lipolysis. Type 1 diabetes accounts for 5–10% of the total diabetes population, the majority of the other patients has type 2 diabetes. Insulin deficiency originates with autoimmune mediated β-cell destruction.
Edith ter Braak, Aline M.E. Stades
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Evolving type 1 diabetes in distinguishing between type 1 and type 2 diabetes
BMJ, 2020Distinguishing between newly diagnosed type 1 or type 2 diabetes can be challenging.1 As a nation, we are becoming more obese, thus increasing predisposition to type 2 diabetes, and we are more often recognising type 1 diabetes in older adults.23 This can blur the lines between type 1 and type 2 diabetes. All relevant factors should be considered when
Neil E. Hill, Nick Oliver
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Nature Immunology, 2001
Type 1 diabetes is preventable in animal models and predictable in humans. The increase in our knowledge of basic immunology has allowed the initiation of large-scale clinical efforts to prevent diabetes.
George S. Eisenbarth +1 more
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Type 1 diabetes is preventable in animal models and predictable in humans. The increase in our knowledge of basic immunology has allowed the initiation of large-scale clinical efforts to prevent diabetes.
George S. Eisenbarth +1 more
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Introduction to Diabetes and Type 1 Diabetes
2016The World Health Organization (WHO) classification of diabetes has been the subject of subtle iterations over the years, with their most recent classification published back in 1985. At that time an expert committee on the diagnosis and classification of diabetes mellitus identified two main types of diabetes: type 1 diabetes (T1D) and type 2 diabetes (
Singh, Prachi +7 more
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Pancreatic β-cells in type 1 and type 2 diabetes mellitus: different pathways to failure
Nature Reviews Endocrinology, 2020D. Eizirik, L. Pasquali, M. Cnop
semanticscholar +1 more source
Nature Reviews Drug Discovery, 2010
Type 1 diabetes (T1D), also termed juvenile-onset or insulin-dependent diabetes, is an autoimmune disease and a metabolic disorder characterized by T-cell-mediated destruction of pancreatic β cells, resulting in insulin deficiency and hyperglycaemia. In 2007, it was reported that 437,500 children were affected by T1D worldwide1.
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Type 1 diabetes (T1D), also termed juvenile-onset or insulin-dependent diabetes, is an autoimmune disease and a metabolic disorder characterized by T-cell-mediated destruction of pancreatic β cells, resulting in insulin deficiency and hyperglycaemia. In 2007, it was reported that 437,500 children were affected by T1D worldwide1.
openaire +2 more sources