Evaluating power and type 1 error in large pedigree analyses of binary traits. [PDF]
PLoS ONE, 2013 Studying population isolates with large, complex pedigrees has many advantages for discovering genetic susceptibility loci; however, statistical analyses can be computationally challenging.
Anna C Cummings +7 more
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Permutation-based significance analysis reduces the type 1 error rate in bisulphite sequencing data analysis of human umbilical cord blood samples [PDF]
Epigenetics, 2022 DNA methylation patterns are largely established in-utero and might mediate the impacts of in-utero conditions on later health outcomes. Associations between perinatal DNA methylation marks and pregnancy-related variables, such as maternal age and ...
Essi Laajala +15 more
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Does raising type 1 error rate improve power to detect interactions in linear regression models? A simulation study. [PDF]
PLoS ONE, 2013 Statistical interactions are a common component of data analysis across a broad range of scientific disciplines. However, the statistical power to detect interactions is often undesirably low.
Casey P Durand
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Type 1 Error on Type 2 Inflammation: Circular Analysis in Asthma Clustering [PDF]
American Journal of Respiratory and Critical Care Medicine, 2023 Brian J. Patchett, Edward S. Schulman
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An Analysis of Differential Bundle Functioning in Multidimensional Tests Using the SIBTEST Procedure
International Journal of Assessment Tools in Education, 2022 This study aims to analyze the differential bundle functioning in multi-dimensional tests with a specific purpose to detect this effect through differentiating the location of the item with DIF in the test, the correlation between the dimensions, the ...
Hülya Kelecioğlu, Didem Özdoğan
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Sample size considerations in research
Endodontology, 2023 “What should be the sample size for my study?” is a common question in the minds of every research at some point of the research cycle. Answering this question with confident is tough even for a seasoned researcher.
Shyam Sivasamy
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Refractive errors in neurofibromatosis type 1 and type 2 [PDF]
British Journal of Ophthalmology, 2007 To document the prevalence of refractive errors in patients with neurofibromatosis type 1 (NF1) and type 2 (NF2) and to compare it with that of age- and sex-matched controls.82 patients with NF1, 21 patients with NF2 and 103 age- and sex-matched controls were evaluated in this prospective observational case-control study. Cycloplegic autorefraction and
Arsen, Akinci +3 more
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Comparison of chronic kidney disease trial designs and analysis strategies [PDF]
Kidney Research and Clinical Practice, 2021 Background Despite the large burden of chronic kidney disease (CKD), it is challenging to conduct adequately powered clinical trials in this setting. Sound and efficient trials are needed to advance treatment.
John Lawrence
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Effects of violating the assumptions of equal variance and independent and identically distributed random variables: A case using {B}ayesian statistical modeling [PDF]
Tutorials in Quantitative Methods for Psychology, 2023 All statistical methods involve assumptions about the data and the output of the methods can be biased when the assumptions are not supported by the data. One of the common assumptions is equal variance across the conditions. Another common assumption is
Sawada, Tadamasa
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Frontiers in Pharmacology, 2021 Using real-world data and past vaccination data, we conducted a large-scale experiment to quantify bias, precision and timeliness of different study designs to estimate historical background (expected) compared to post-vaccination (observed) rates of ...
Xintong Li +21 more
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